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Ub-SCNN1G [plasma membrane]
Stable Identifier
R-HSA-2684953
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Amiloride-sensitive sodium channel subunit gamma, SCNNG_HUMAN, Ubiquitinated-SCNN1G
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Homo sapiens)
Ub-SCNN channels [plasma membrane] (Homo sapiens)
Ub-SCNN1G [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51170 SCNN1G
Gene Names
SCNN1G
Chain
chain:1-649
Reference Genes
BioGPS Gene:6340 SCNN1G
COSMIC (genes):SCNN1G SCNN1G
CTD Gene:6340 SCNN1G
dbSNP Gene:6340 SCNN1G
ENSEMBL:ENSG00000166828 SCNN1G
ENSEMBL_homo_sapiens_GENE:ENSG00000166828.3 SCNN1G
HGNC:10602 SCNN1G
KEGG Gene (Homo sapiens):6340 SCNN1G
Monarch:6340 SCNN1G
NCBI Gene:6340 SCNN1G
OMIM:600761 SCNN1G
UCSC:P51170 SCNN1G
Reference Transcript
RefSeq:NM_001039.3 SCNN1G
Other Identifiers
11731973_at
11731974_at
16816962
241436_PM_at
241436_at
3652869
3652870
3652871
3652873
3652874
3652875
3652877
3652881
3652882
3652883
3652884
3652885
3652886
3652887
3652888
3652889
3652890
3652892
6340
7994058
80001_at
GE60111
GO:0003013
GO:0005215
GO:0005216
GO:0005272
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005886
GO:0006811
GO:0006814
GO:0006883
GO:0008217
GO:0009897
GO:0015280
GO:0016020
GO:0016324
GO:0034220
GO:0034706
GO:0035725
GO:0043226
GO:0050699
GO:0050877
GO:0050891
GO:0050896
GO:0050909
GO:0050914
GO:0050915
GO:0055065
GO:0055078
GO:0055085
GO:0070062
GO:0071468
GO:0098662
GO:0098719
GO:1904045
GO:1904117
HMNXSV003051622
Hs.145645.0.A1_3p_at
ILMN_1814215
ILMN_2153837
PH_hs_0022603
TC16000253.hg
U48936_at
g4506820_3p_s_at
Participates
as a component of
Ub-SCNN channels [plasma membrane] (Homo sapiens)
Other forms of this molecule
SCNN1G [plasma membrane]
Inferred To
del-3 [plasma membrane]
(Caenorhabditis elegans)
egas-3 [plasma membrane]
(Caenorhabditis elegans)
del-6 [plasma membrane]
(Caenorhabditis elegans)
asic-1 [plasma membrane]
(Caenorhabditis elegans)
scnn1g [plasma membrane]
(Xenopus tropicalis)
SCNN1G [plasma membrane]
(Bos taurus)
SCNN1G [plasma membrane]
(Canis familiaris)
SCNN1G [plasma membrane]
(Gallus gallus)
SCNN1G [plasma membrane]
(Sus scrofa)
egas-1 [plasma membrane]
(Caenorhabditis elegans)
asic-2 [plasma membrane]
(Caenorhabditis elegans)
degt-1 [plasma membrane]
(Caenorhabditis elegans)
egas-4 [plasma membrane]
(Caenorhabditis elegans)
unc-8 [plasma membrane]
(Caenorhabditis elegans)
Homologues of Ub-SCNN1G [plasma membrane]
(Caenorhabditis elegans)
Scnn1g [plasma membrane]
(Mus musculus)
Scnn1g [plasma membrane]
(Rattus norvegicus)
mec-10 [plasma membrane]
(Caenorhabditis elegans)
unc-105 [plasma membrane]
(Caenorhabditis elegans)
deg-1 [plasma membrane]
(Caenorhabditis elegans)
egas-2 [plasma membrane]
(Caenorhabditis elegans)
mec-4 [plasma membrane]
(Caenorhabditis elegans)
del-1 [plasma membrane]
(Caenorhabditis elegans)
del-4 [plasma membrane]
(Caenorhabditis elegans)
Modified Residues
Name
ubiquitinylated lysine (polyubiquitin (linkage unknown) [plasma membrane]) at unknown position
Modification
polyubiquitin (linkage unknown) [plasma membrane]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_001030.2
Guide to Pharmacology - Targets
741
OpenTargets
ENSG00000166828
GeneCards
P51170
HPA
ENSG00000166828-SCNN1G
Ensembl
ENSG00000166828
,
ENST00000300061
,
ENSP00000300061
PRO
P51170
Pharos - Targets
P51170
Orphanet
15258
HMDB Protein
HMDBP02930
PDB
6WTH
,
6BQN
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