Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
EPHA5 [plasma membrane]
Stable Identifier
R-HSA-2682335
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ephrin type-A receptor 5 ecNumber2.7.10.1/ecNumber, EPHA5_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH receptors autophosphorylate (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
ADAM10 cleaves EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs:ADAM10 [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPH:EFN dimers tetramerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPH:EFN tetramers oligomerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPHAs bind EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P54756 EPHA5
Gene Names
EPHA5, BSK, EHK1, HEK7, TYRO4
Chain
signal peptide:1-24, chain:25-1037
Reference Genes
BioGPS Gene:2044 EPHA5
COSMIC (genes):EPHA5 EPHA5
CTD Gene:2044 EPHA5
dbSNP Gene:2044 EPHA5
ENSEMBL:ENSG00000145242 EPHA5
HGNC:3389 EPHA5
KEGG:hsa:2044 EPHA5
Monarch:2044 EPHA5
NCBI Gene:2044 EPHA5
OMIM:600004 EPHA5
UCSC:P54756 EPHA5
Reference Transcript
RefSeq:NM_001318761.1 EPHA5
RefSeq:NM_001281766.2 EPHA5
RefSeq:NM_182472.4 EPHA5
RefSeq:NM_004439.7 EPHA5
RefSeq:NM_001281765.2 EPHA5
Other Identifiers
11730142_a_at
11730143_a_at
1604_at
1605_g_at
16976329
2044
215664_PM_s_at
215664_s_at
237939_PM_at
237939_at
2771343
2771344
2771345
2771346
2771348
2771349
2771350
2771351
2771356
2771357
2771359
2771361
2771364
2771367
2771372
2771374
2771377
2771379
2771388
2771394
2771411
2771412
2771415
2771416
2771425
2771426
34564_at
8100578
88944_at
A_23_P147839
A_32_P149640
GE892980
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005003
GO:0005004
GO:0005005
GO:0005515
GO:0005524
GO:0005783
GO:0005791
GO:0005886
GO:0006355
GO:0006468
GO:0007169
GO:0007399
GO:0007411
GO:0009897
GO:0016020
GO:0016740
GO:0019933
GO:0021766
GO:0030424
GO:0030425
GO:0032793
GO:0032956
GO:0042995
GO:0043025
GO:0043087
GO:0043226
GO:0048013
GO:0048471
GO:0048666
GO:0048856
GO:0060089
GO:0061178
GO:0140096
HMNXSV003017773
HMNXSV003044382
Hs.202436.0.A1_3p_at
Hs.31092.1.S1_3p_a_at
ILMN_1668022
ILMN_1767342
ILMN_2402874
L36644_at
PH_hs_0022996
TC04001245.hg
X95425_s_at
Participates
as a member of
EPHAs [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y650,Y656-EPHA5 [plasma membrane]
Inferred To
EPHA5 [plasma membrane]
(Bos taurus)
EPHA5 [plasma membrane]
(Canis familiaris)
EPHA5 [plasma membrane]
(Gallus gallus)
EPHA5 [plasma membrane]
(Rattus norvegicus)
EPHA5 [plasma membrane]
(Sus scrofa)
EPHA5 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001268694.1
,
NP_001268695.1
,
NP_001305690.1
,
NP_004430.4
,
NP_872272.2
ZINC - World Drugs
EPHA5_HUMAN
Guide to Pharmacology - Targets
1825
ENSEMBL
ENST00000354839
,
ENSP00000273854
,
ENST00000273854
,
ENSP00000346899
OpenTargets
ENSG00000145242
ZINC - FDA approved
EPHA5_HUMAN
ZINC - Substances
EPHA5_HUMAN
ZINC - Biogenic
EPHA5_HUMAN
ZINC target
P54756
PRO
P54756
GlyGen
P54756
PDB
4ET7
,
2R2P
ZINC - Investigational
EPHA5_HUMAN
HPA
ENSG00000145242-EPHA5
Pharos - Targets
P54756
ZINC - Predictions - Purchasable
EPHA5_HUMAN
HMDB Protein
HMDBP01168
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text