Reactome | EPHA6 [plasma membrane]

EPHA6 [plasma membrane]

Stable Identifier

R-HSA-2682332

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ephrin type-A receptor 6 ecNumber2.7.10.1/ecNumber, EPHA6_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UF33 EPHA6

Gene Names

EPHA6, EHK2, HEK12

Chain

signal peptide:1-22, chain:23-1036

Reference Genes

BioGPS Gene:285220 EPHA6

COSMIC (genes):EPHA6 EPHA6

CTD Gene:285220 EPHA6

dbSNP Gene:285220 EPHA6

ENSEMBL:ENSG00000080224 EPHA6

HGNC:19296 EPHA6

KEGG:hsa:285220 EPHA6

Monarch:285220 EPHA6

NCBI Gene:285220 EPHA6

OMIM:600066 EPHA6

UCSC:Q9UF33 EPHA6

Reference Transcript

Other Identifiers

11740830_a_at

11740831_at

11750366_a_at

11753206_a_at

11762144_at

1561396_PM_at

1561396_at

233095_PM_at

233095_at

233184_PM_at

233184_at

2632780

2632781

2632782

2632789

2632800

2632801

2632809

2632810

2632825

2632826

2632828

2632829

2632831

2632845

2632848

2632849

2632850

2632854

2632855

2632859

2632860

2632863

2632864

2632866

2632870

2632876

2632878

2632880

2632881

2632882

2632883

2632897

2632898

2632903

2632904

2632906

2632907

2632908

2632909

2632910

2632911

2632912

2632914

2632916

2632918

2632920

2632921

2632922

2632923

2632924

2632925

2632926

2632927

285220

8081138

89344_at

A_14_P101180

A_14_P131911

A_14_P136180

A_14_P136397

A_23_P18342

A_33_P3408782

GE486085

GE56651

GE733402

GE893070

GO:0003674

GO:0003824

GO:0004672

GO:0004713

GO:0004714

GO:0005003

GO:0005005

GO:0005515

GO:0005524

GO:0005654

GO:0005886

GO:0006468

GO:0007169

GO:0007411

GO:0008150

GO:0016020

GO:0016740

GO:0030425

GO:0048013

GO:0060089

GO:0140096

HMNXSV003004830

HMNXSV003014669

HMNXSV003017141

HMNXSV003025804

HMNXSV003040928

Hs.145172.0.S1_3p_at

Hs.272208.0.S1_3p_at

Hs2.256916.1.S1_3p_s_at

ILMN_1654979

ILMN_1657349

ILMN_1666469

ILMN_1690814

ILMN_1703325

ILMN_1719531

ILMN_1750488

ILMN_2371119

PH_hs_0014027

PH_hs_0027865

PH_hs_0037638

TC03000478.hg

TC03002426.hg

p11887

Participates

as a member of

EPHAs [plasma membrane] (Homo sapiens)

Other forms of this molecule

p-Y606,Y612-EPHA6 [plasma membrane]

Inferred To

EPHA6 [plasma membrane] (Mus musculus)

EPHA6 [plasma membrane] (Rattus norvegicus)

EPHA6 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_775926.1, NP_001265229.1

ZINC - World Drugs

EPHA6_HUMAN

Guide to Pharmacology - Targets

1826

ENSEMBL

ENST00000502694, ENSP00000423950, ENST00000514100, ENSP00000421711

OpenTargets

ENSG00000080224

ZINC - FDA approved

EPHA6_HUMAN

ZINC - Substances

EPHA6_HUMAN

ZINC - Biogenic

EPHA6_HUMAN

ZINC target

Q9UF33

PRO

Q9UF33

GlyGen

Q9UF33

ZINC - Investigational

EPHA6_HUMAN

HPA

ENSG00000080224-EPHA6

Pharos - Targets

Q9UF33

ZINC - Predictions - Purchasable

EPHA6_HUMAN

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04070 PROC	13	PROC [endoplasmic reticulum lumen] (R-HSA-8956772) p-PROC [endoplasmic reticulum lumen] (R-HSA-8957067) 8xCbxE-3D-PROC(43-197) [extracellular region] (R-HSA-141041) PROC(212-461) [extracellular region] (R-HSA-141048) PROC(200-461) [extracellular region] (R-HSA-141042) PROC(200-211) [extracellular region] (R-HSA-141051) 8xCbxE-3D-PROC(33-197) [endoplasmic reticulum lumen] (R-HSA-159730) PROC(200-461) [endoplasmic reticulum lumen] (R-HSA-159780) 8xCbxE-3D-PROC(33-197) [Golgi lumen] (R-HSA-159747) PROC(200-461) [Golgi lumen] (R-HSA-159827) 3D-PROC(33-197) [endoplasmic reticulum lumen] (R-HSA-159768) PROC(33-42) [Golgi lumen] (R-HSA-159779) 8xCbxE-3D-PROC(43-197) [Golgi lumen] (R-HSA-159756)	0.527	2
UniProt:Q01523 DEFA5	5	DEFA5(1-94) [Golgi lumen] (R-HSA-1467267) DEFA5(20-94) [Golgi lumen] (R-HSA-1467208) DEFA5(20-94) [secretory granule lumen] (R-HSA-1471358) DEFA5(20-94) [extracellular region] (R-HSA-1471344) DEFA5(?-94) [extracellular region] (R-HSA-1462017)	0.527	2