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EPHA3 [plasma membrane]
Stable Identifier
R-HSA-2682317
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ephrin type-A receptor 3 ecNumber2.7.10.1/ecNumber, EPHA3_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH receptors autophosphorylate (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
ADAM10 cleaves EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs:ADAM10 [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPH:EFN dimers tetramerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPH:EFN tetramers oligomerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPHAs bind EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P29320 EPHA3
Gene Names
EPHA3, ETK, ETK1, HEK, TYRO4
Chain
signal peptide:1-20, chain:21-983
Reference Genes
BioGPS Gene:2042 EPHA3
COSMIC (genes):EPHA3 EPHA3
CTD Gene:2042 EPHA3
dbSNP Gene:2042 EPHA3
ENSEMBL:ENSG00000044524 EPHA3
HGNC:3387 EPHA3
KEGG:hsa:2042 EPHA3
Monarch:2042 EPHA3
NCBI Gene:2042 EPHA3
OMIM:179611 EPHA3
UCSC:P29320 EPHA3
Reference Transcript
RefSeq:NM_182644.2 EPHA3
RefSeq:NM_005233.5 EPHA3
Other Identifiers
11727582_a_at
11727583_a_at
11738240_at
1234_at
16942958
2042
206070_PM_s_at
206070_s_at
206071_PM_s_at
206071_s_at
211164_3p_at
211164_PM_at
211164_at
2632248
2632249
2632250
2632251
2632252
2632253
2632259
2632268
2632275
2632276
2632277
2632278
2632279
2632290
2632291
2632292
2632295
2632296
2632299
2632303
2632308
2632309
2632310
2632315
2632316
2632319
2632320
2632321
2632322
2632323
2632324
58771_at
8081081
A_14_P121187
A_14_P122484
A_14_P131068
A_14_P137413
A_23_P147046
A_23_P169819
A_24_P254744
GE62676
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005003
GO:0005004
GO:0005005
GO:0005515
GO:0005524
GO:0005576
GO:0005654
GO:0005768
GO:0005769
GO:0005829
GO:0005856
GO:0005886
GO:0006468
GO:0007155
GO:0007169
GO:0007411
GO:0010717
GO:0010976
GO:0015629
GO:0016020
GO:0016477
GO:0016740
GO:0018108
GO:0030425
GO:0031410
GO:0031965
GO:0032956
GO:0043087
GO:0043226
GO:0045806
GO:0048013
GO:0048870
GO:0051893
GO:0060089
GO:0070507
GO:0071300
GO:0097155
GO:0097156
GO:0140096
GO:1903078
HMNXSV003033490
HMNXSV003056414
ILMN_1775931
ILMN_1782076
ILMN_2286574
M83941_at
PH_hs_0006956
TC03000468.hg
g12003434_3p_a_at
g12003436_3p_at
g12003436_3p_x_at
g4885210_3p_a_at
Participates
as a member of
EPHAs [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y596,Y602-EPHA3 [plasma membrane]
Inferred To
Epha3 [plasma membrane]
(Mus musculus)
EPHA3 [plasma membrane]
(Bos taurus)
EPHA3 [plasma membrane]
(Canis familiaris)
EPHA3 [plasma membrane]
(Gallus gallus)
EPHA3 [plasma membrane]
(Rattus norvegicus)
EPHA3 [plasma membrane]
(Sus scrofa)
EPHA3 [plasma membrane]
(Xenopus tropicalis)
Cross References
Guide to Pharmacology - Targets
1823
OpenTargets
ENSG00000044524
ENSEMBL
ENST00000336596
,
ENST00000452448
,
ENSP00000337451
,
ENSG00000044524
,
ENSP00000399926
ZINC - FDA approved
EPHA3_HUMAN
ZINC - Substances
EPHA3_HUMAN
ZINC - Biogenic
EPHA3_HUMAN
ZINC target
P29320
PRO
P29320
GlyGen
P29320
PDB
4GK2
,
4GK3
,
4P5Q
,
4L0P
,
4GK4
,
2QOB
,
2QOD
,
2QOC
,
2QOF
,
3DZQ
,
4TWO
,
4P5Z
,
2QO2
,
2QO7
,
4TWN
,
2QOL
,
2QOI
,
2QON
,
2QOO
,
2QOK
,
2QOQ
,
6IN0
,
3FXX
,
4P4C
,
2GSF
,
4G2F
,
2QO9
,
3FY2
ZINC - Investigational
EPHA3_HUMAN
HPA
ENSG00000044524-EPHA3
GeneCards
EPHA3
Pharos - Targets
P29320
ZINC - Predictions - Purchasable
EPHA3_HUMAN
HMDB Protein
HMDBP01368
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