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NOTCH1 L1574P [plasma membrane]
Stable Identifier
R-HSA-2681760
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by NOTCH1 in Cancer (Homo sapiens)
Signaling by NOTCH1 HD Domain Mutants in Cancer (Homo sapiens)
Constitutive Signaling by NOTCH1 HD Domain Mutants (Homo sapiens)
NOTCH1 HD domain mutants are cleaved to produce NEXT1 irrespective of ligand binding (Homo sapiens)
NOTCH1 HD domain mutants/Ub-DLL/JAG:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
Ub-DLL/JAG:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
DLL/JAG:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
DLL1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
DLL4:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
JAG1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
JAG2:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants bind DLL1 (Homo sapiens)
DLL1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants bind DLL4 (Homo sapiens)
DLL4:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants bind JAG1 (Homo sapiens)
JAG1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants bind JAG2 (Homo sapiens)
JAG2:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants (Homo sapiens)
DLL/JAG:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
DLL1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
DLL4:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
JAG1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
JAG2:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
Ub-DLL/JAG:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
DLL/JAG:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
DLL1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
DLL4:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
JAG1:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
JAG2:NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
NOTCH1 L1574P [plasma membrane] (Homo sapiens)
Participants
components
NOTCH1 L1574P Extracellular Fragment [extracellular region]
(Homo sapiens)
NOTCH1(1665-2555) [plasma membrane]
(Homo sapiens)
Participates
as a candidate of
NOTCH1 HD domain mutants [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
T-cell acute lymphoblastic leukemia
DOID:5603
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