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SCNN1B [plasma membrane]
Stable Identifier
R-HSA-2671900
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Amiloride-sensitive sodium channel subunit beta, SCNNB_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of salty taste (Homo sapiens)
SCNN channels transport extracellular Na+ to cytosol (Homo sapiens)
SCNN channels [plasma membrane] (Homo sapiens)
SCNN1B [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Homo sapiens)
SCNN channels [plasma membrane] (Homo sapiens)
SCNN1B [plasma membrane] (Homo sapiens)
Ub-SCNN channels [plasma membrane] (Homo sapiens)
SCNN1B [plasma membrane] (Homo sapiens)
SCNN channels transport extracellular Na+ to cytosol (Homo sapiens)
SCNN channels [plasma membrane] (Homo sapiens)
SCNN1B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51168 SCNN1B
Gene Names
SCNN1B
Chain
chain:1-640
Reference Genes
BioGPS Gene:6338 SCNN1B
COSMIC (genes):SCNN1B SCNN1B
CTD Gene:6338 SCNN1B
dbSNP Gene:6338 SCNN1B
ENSEMBL:ENSG00000168447 SCNN1B
ENSEMBL_homo_sapiens_GENE:ENSG00000168447.11 SCNN1B
HGNC:10600 SCNN1B
KEGG Gene (Homo sapiens):6338 SCNN1B
Monarch:6338 SCNN1B
NCBI Gene:6338 SCNN1B
OMIM:600760 SCNN1B
UCSC:P51168 SCNN1B
Reference Transcript
RefSeq:NM_000336.2 SCNN1B
Other Identifiers
11721417_at
16816978
205464_PM_at
205464_at
3652907
3652909
3652913
3652921
3652922
3652924
3652926
3652927
3652931
3652933
3652934
3652938
3652940
3652941
3652943
3652944
3652945
3652946
39682_at
6338
7994074
A_14_P122904
A_24_P306499
A_32_P83098
GE60110
GO:0002269
GO:0002283
GO:0002376
GO:0003012
GO:0003013
GO:0003014
GO:0005215
GO:0005272
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006629
GO:0006811
GO:0006814
GO:0006883
GO:0006954
GO:0008217
GO:0009410
GO:0009897
GO:0010467
GO:0014824
GO:0015280
GO:0016020
GO:0016324
GO:0030659
GO:0031410
GO:0032094
GO:0032341
GO:0034101
GO:0034220
GO:0034706
GO:0035264
GO:0035725
GO:0042045
GO:0043226
GO:0050699
GO:0050877
GO:0050891
GO:0050896
GO:0050909
GO:0050914
GO:0050915
GO:0055065
GO:0055075
GO:0055078
GO:0055085
GO:0070062
GO:0070254
GO:0070944
GO:0071468
GO:0098542
GO:0098662
GO:0098719
GO:1904045
GO:1904117
HMNXSV003002352
ILMN_1740917
PH_hs_0002940
TC16000254.hg
TC16001455.hg
X87159_at
g4506816_3p_at
p26713
Participates
as a component of
Ub-SCNN channels [plasma membrane] (Homo sapiens)
SCNN channels [plasma membrane] (Homo sapiens)
Inferred To
Homologues of SCNN1B [plasma membrane]
(Caenorhabditis elegans)
SCNN1B [plasma membrane]
(Bos taurus)
SCNN1B [plasma membrane]
(Canis familiaris)
SCNN1B [plasma membrane]
(Gallus gallus)
SCNN1B [plasma membrane]
(Sus scrofa)
del-3 [plasma membrane]
(Caenorhabditis elegans)
egas-3 [plasma membrane]
(Caenorhabditis elegans)
del-6 [plasma membrane]
(Caenorhabditis elegans)
Scnn1b [plasma membrane]
(Mus musculus)
Scnn1b [plasma membrane]
(Rattus norvegicus)
asic-1 [plasma membrane]
(Caenorhabditis elegans)
egas-1 [plasma membrane]
(Caenorhabditis elegans)
asic-2 [plasma membrane]
(Caenorhabditis elegans)
degt-1 [plasma membrane]
(Caenorhabditis elegans)
egas-4 [plasma membrane]
(Caenorhabditis elegans)
unc-8 [plasma membrane]
(Caenorhabditis elegans)
mec-10 [plasma membrane]
(Caenorhabditis elegans)
unc-105 [plasma membrane]
(Caenorhabditis elegans)
deg-1 [plasma membrane]
(Caenorhabditis elegans)
scnn1b [plasma membrane]
(Xenopus tropicalis)
egas-2 [plasma membrane]
(Caenorhabditis elegans)
mec-4 [plasma membrane]
(Caenorhabditis elegans)
del-1 [plasma membrane]
(Caenorhabditis elegans)
del-4 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_000327.2
Guide to Pharmacology - Targets
739
OpenTargets
ENSG00000168447
HPA
ENSG00000168447-SCNN1B
GeneCards
P51168
Ensembl
ENST00000343070
,
ENSP00000345751
,
ENST00000307331
,
ENSG00000168447
,
ENSP00000302874
PRO
P51168
Pharos - Targets
P51168
Orphanet
15257
HMDB Protein
HMDBP09092
PDB
6WTH
,
6BQN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P46934 NEDD4
1
NEDD4 [cytosol]
(R-HSA-975992)
0.719
5
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