Reactome | SCN11A [plasma membrane]

SCN11A [plasma membrane]

Stable Identifier

R-HSA-2671896

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Sodium channel protein type 11 subunit alpha, SCNBA_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - L1CAM interactions (Homo sapiens)
      - Interaction between L1 and Ankyrins (Homo sapiens)
        
        Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
        
        KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
        
        SCNAs:SCNBs [plasma membrane] (Homo sapiens)
        
        SCNAs [plasma membrane] (Homo sapiens)
        
        SCN11A [plasma membrane] (Homo sapiens)
        
        NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
        
        KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
        
        SCNAs:SCNBs [plasma membrane] (Homo sapiens)
        
        SCNAs [plasma membrane] (Homo sapiens)
        
        SCN11A [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UI33 SCN11A

Gene Names

SCN11A, SCN12A, SNS2

Chain

chain:1-1791

Reference Genes

BioGPS Gene:11280 SCN11A

COSMIC (genes):SCN11A SCN11A

CTD Gene:11280 SCN11A

dbSNP Gene:11280 SCN11A

ENSEMBL:ENSG00000168356.13 SCN11A

HGNC:10583 SCN11A

KEGG Gene (Homo sapiens):11280 SCN11A

Monarch:11280 SCN11A

NCBI Gene:11280 SCN11A

OMIM:604385 SCN11A

UCSC:Q9UI33 SCN11A

Reference Transcript

Other Identifiers

11280

11740800_x_at

11761862_at

16952349

210853_PM_at

210853_at

220791_PM_x_at

220791_x_at

224029_PM_x_at

224029_x_at

2669804

2669805

2669806

2669807

2669808

2669809

2669810

2669811

2669812

2669813

2669814

2669815

2669816

2669818

2669819

2669820

2669821

2669822

2669823

2669824

2669825

2669827

2669828

2669829

2669830

2669831

2669832

2669833

2669834

2669835

2669837

2669838

2669839

2669842

2669843

2669846

2669848

2669849

2669850

2669851

2669853

2669854

2669855

2669856

2669857

2669858

2669859

2669862

2669865

2669866

2669867

2669876

2669877

8086283

A_24_P393181

GO:0001518

GO:0005215

GO:0005216

GO:0005244

GO:0005248

GO:0005261

GO:0005272

GO:0005576

GO:0005615

GO:0005886

GO:0006811

GO:0006814

GO:0009410

GO:0016020

GO:0016021

GO:0019228

GO:0023052

GO:0030424

GO:0032991

GO:0034765

GO:0035725

GO:0043226

GO:0044299

GO:0050877

GO:0051649

GO:0051930

GO:0055085

GO:0070062

GO:0086010

HMNXSV003051625

ILMN_1797892

PH_hs_0010939

TC03001300.hg

g6572949_3p_s_at

g6693704_3p_at

g7657541_3p_at

Participates

as a candidate of

SCNAs [plasma membrane] (Homo sapiens)

Inferred To

SCN11A [plasma membrane] (Bos taurus)

scn2a [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_016861138.1, NP_054858.2, NP_001274152.1, XP_016861139.1

Guide to Pharmacology - Targets

586

OpenTargets

ENSG00000168356

ZINC - Substances

SCNBA_HUMAN

ZINC target

Q9UI33

ZINC - Biogenic

SCNBA_HUMAN

PRO

Q9UI33

HPA

ENSG00000168356-SCN11A

GeneCards

Q9UI33

Ensembl

ENST00000668754, ENST00000456224, ENSP00000307599, ENST00000444237, ENST00000302328, ENSP00000416757, ENSP00000499569, ENSG00000168356, ENSP00000408028

Pharos - Targets

Q9UI33

ZINC - Predictions - Purchasable

SCNBA_HUMAN

Orphanet

21899

HMDB Protein

HMDBP09091