Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SCN11A [plasma membrane]
Stable Identifier
R-HSA-2671896
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sodium channel protein type 11 subunit alpha, SCNBA_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs [plasma membrane] (Homo sapiens)
SCN11A [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs [plasma membrane] (Homo sapiens)
SCN11A [plasma membrane] (Homo sapiens)
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 0 - rapid depolarisation (Homo sapiens)
SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs [plasma membrane] (Homo sapiens)
SCN11A [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UI33 SCN11A
Gene Names
SCN11A, SCN12A, SNS2
Chain
chain:1-1791
Reference Genes
BioGPS Gene:11280 SCN11A
COSMIC (genes):SCN11A SCN11A
CTD Gene:11280 SCN11A
dbSNP Gene:11280 SCN11A
ENSEMBL:ENSG00000168356 SCN11A
HGNC:10583 SCN11A
KEGG:hsa:11280 SCN11A
Monarch:11280 SCN11A
NCBI Gene:11280 SCN11A
OMIM:604385 SCN11A
UCSC:Q9UI33 SCN11A
Reference Transcript
RefSeq:XM_017005650.1 SCN11A
RefSeq:NM_001287223.1 SCN11A
RefSeq:XM_017005649.1 SCN11A
RefSeq:NM_014139.2 SCN11A
Other Identifiers
11280
11740800_x_at
11761862_at
16952349
16952379
210853_PM_at
210853_at
220791_PM_x_at
220791_x_at
224029_PM_x_at
224029_x_at
2669804
2669805
2669806
2669807
2669808
2669809
2669810
2669811
2669812
2669813
2669814
2669815
2669816
2669818
2669819
2669820
2669821
2669822
2669823
2669824
2669825
2669827
2669828
2669829
2669830
2669831
2669832
2669833
2669834
2669835
2669837
2669838
2669839
2669842
2669843
2669846
2669848
2669849
2669850
2669851
2669853
2669854
2669855
2669856
2669857
2669858
2669859
2669860
2669861
2669862
2669865
2669866
2669867
2669876
2669877
8086283
A_21_P0003112
A_24_P393181
GO:0001508
GO:0001518
GO:0001966
GO:0002376
GO:0002526
GO:0002544
GO:0003012
GO:0003014
GO:0005215
GO:0005216
GO:0005248
GO:0005261
GO:0005272
GO:0005886
GO:0006811
GO:0006814
GO:0006954
GO:0007186
GO:0007409
GO:0007623
GO:0007635
GO:0009408
GO:0009409
GO:0009410
GO:0009636
GO:0009644
GO:0010737
GO:0010996
GO:0016020
GO:0016192
GO:0019226
GO:0019228
GO:0019233
GO:0030424
GO:0034220
GO:0034695
GO:0034702
GO:0035725
GO:0040040
GO:0042391
GO:0043025
GO:0043226
GO:0043303
GO:0044295
GO:0044297
GO:0044299
GO:0046873
GO:0048265
GO:0048266
GO:0048856
GO:0048870
GO:0050877
GO:0050965
GO:0050966
GO:0050974
GO:0051649
GO:0055085
GO:0060004
GO:0060073
GO:0060538
GO:0060840
GO:0061367
GO:0061368
GO:0070062
GO:0070417
GO:0070588
GO:0071731
GO:0086002
GO:0086010
GO:0098655
GO:0098662
GO:0099610
GO:0160025
GO:1990408
GO:1990770
HMNXSV003045887
HMNXSV003051625
ILMN_1797892
PH_hs_0010939
TC03001300.hg
TC03002865.hg
g6572949_3p_s_at
g6693704_3p_at
g7657541_3p_at
p21845
p21846
Participates
as a candidate of
SCNAs [plasma membrane] (Homo sapiens)
Inferred To
SCN11A [plasma membrane]
(Bos taurus)
Cross References
Guide to Pharmacology - Targets
586
ENSEMBL
ENSP00000307599
,
ENSG00000168356
,
ENST00000456224
,
ENSP00000499569
,
ENST00000444237
,
ENST00000668754
,
ENSP00000416757
,
ENSP00000408028
,
ENST00000302328
OpenTargets
ENSG00000168356
ZINC - Substances
SCNBA_HUMAN
ZINC - Biogenic
SCNBA_HUMAN
ZINC target
Q9UI33
PRO
Q9UI33
GlyGen
Q9UI33
GeneCards
SCN11A
HPA
ENSG00000168356-SCN11A
Pharos - Targets
Q9UI33
Orphanet
SCN11A
ZINC - Predictions - Purchasable
SCNBA_HUMAN
HMDB Protein
HMDBP09091
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text