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ASIC1 [plasma membrane]
Stable Identifier
R-HSA-2671890
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Acid-sensing ion channel 1, ASIC1_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
ASIC trimers bind H+ (Homo sapiens)
ASIC trimers [plasma membrane] (Homo sapiens)
ASIC1 trimer [plasma membrane] (Homo sapiens)
ASIC1 [plasma membrane] (Homo sapiens)
ASIC trimers:H+ [plasma membrane] (Homo sapiens)
ASIC1 trimer:H+ [plasma membrane] (Homo sapiens)
ASIC1 [plasma membrane] (Homo sapiens)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Homo sapiens)
ASIC trimers:H+ [plasma membrane] (Homo sapiens)
ASIC1 trimer:H+ [plasma membrane] (Homo sapiens)
ASIC1 [plasma membrane] (Homo sapiens)
ASICs bind STOML3, (STOM) (Homo sapiens)
ASIC trimers:H+ [plasma membrane] (Homo sapiens)
ASIC1 trimer:H+ [plasma membrane] (Homo sapiens)
ASIC1 [plasma membrane] (Homo sapiens)
ASIC trimers:H+:STOML3,(STOM) [plasma membrane] (Homo sapiens)
ASIC trimers:H+ [plasma membrane] (Homo sapiens)
ASIC1 trimer:H+ [plasma membrane] (Homo sapiens)
ASIC1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P78348 ASIC1
Gene Names
ASIC1, ACCN2, BNAC2
Chain
chain:1-528
Reference Genes
BioGPS Gene:41 ASIC1
COSMIC (genes):ASIC1 ASIC1
CTD Gene:41 ASIC1
dbSNP Gene:41 ASIC1
ENSEMBL:ENSG00000110881 ASIC1
HGNC:100 ASIC1
KEGG:hsa:41 ASIC1
Monarch:41 ASIC1
NCBI Gene:41 ASIC1
OMIM:602866 ASIC1
UCSC:P78348 ASIC1
Reference Transcript
RefSeq:NM_001095.3 ASIC1
RefSeq:NM_001256830.1 ASIC1
RefSeq:NM_020039.3 ASIC1
Other Identifiers
11729959_a_at
11746958_s_at
11752092_s_at
16750996
205156_PM_s_at
205156_s_at
3414359
3414361
3414362
3414366
3414367
3414368
3414369
3414370
3414371
3414372
3414373
3414374
3414375
3414376
3414377
3414378
3414379
3414381
3414382
3414383
3414384
3414385
3414386
3414387
3414388
3414389
3414391
3414392
3414393
3414394
3414395
3414396
3414397
3666238
37953_PM_s_at
37953_s_at
41
7955317
A_14_P128283
A_23_P204751
GE61482
GO:0001662
GO:0001975
GO:0005215
GO:0005216
GO:0005261
GO:0005272
GO:0005515
GO:0005794
GO:0005886
GO:0006812
GO:0006814
GO:0006816
GO:0007269
GO:0007613
GO:0008306
GO:0009986
GO:0010447
GO:0015276
GO:0015280
GO:0016020
GO:0022839
GO:0022890
GO:0034220
GO:0035725
GO:0042391
GO:0043226
GO:0045202
GO:0046929
GO:0050877
GO:0050915
GO:0051649
GO:0055085
GO:0065003
GO:0070207
GO:0070588
GO:0071467
GO:0098662
GO:0098793
GO:0098839
GO:0098978
GO:0150052
GO:0160128
HMNXSV003014842
ILMN_1727251
ILMN_1769694
PH_hs_0014150
TC12000386.hg
U78180_at
g9943845_3p_s_at
Participates
as a component of
ASIC1 trimer [plasma membrane] (Homo sapiens)
ASIC1 trimer:H+ [plasma membrane] (Homo sapiens)
Inferred To
asic1 [plasma membrane]
(Xenopus tropicalis)
ASIC1 [plasma membrane]
(Bos taurus)
ASIC1 [plasma membrane]
(Canis familiaris)
ASIC1 [plasma membrane]
(Gallus gallus)
ASIC1 [plasma membrane]
(Sus scrofa)
asic1a [plasma membrane]
(Danio rerio)
Asic1 [plasma membrane]
(Mus musculus)
Asic1 [plasma membrane]
(Rattus norvegicus)
del-9 [plasma membrane]
(Caenorhabditis elegans)
ppk26 [plasma membrane]
(Drosophila melanogaster)
Cross References
Guide to Pharmacology - Targets
684
ENSEMBL
ENSP00000450247
,
ENST00000228468
,
ENST00000552438
,
ENST00000447966
,
ENSP00000400228
,
ENSP00000228468
OpenTargets
ENSG00000110881
HPA
ENSG00000110881-ASIC1
ZINC target
P78348
PRO
P78348
Pharos - Targets
P78348
GlyGen
P78348
HMDB Protein
HMDBP09053
PDB
7CFT
,
6L6I
,
6L6N
,
7CFS
,
7RNN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.655
4
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