Phosphorylated STAT3 Dissociates from Leptin Receptor

Stable Identifier
R-HSA-2671839
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
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Phosphorylated STAT3 Dissociates from Leptin Receptor
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Phosphorylated STAT3 dissociates from LEPR in the LEP:LEPR:JAK2 complex, dimerizes, and translocates to the nucleus.

Literature References
PubMed ID Title Journal Year
9405487 Divergent signaling capacities of the long and short isoforms of the leptin receptor

da Silva, B, Uotani, S, Flier, JS, Bjørbaek, C

J. Biol. Chem. 1997
Participants
Input
Output
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as an event of
Inferred From
Phosphorylated Stat3 Dissociates from Leptin Receptor (Mus musculus)
Authored
May, B  (2012-11-24)
Reviewed
Scherer, T  (2013-08-31)
Gonzalez-Perez, RR  (2013-10-26)
Created
May, B  (2012-11-26)
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