Reactome | DPEP2 [plasma membrane]

DPEP2 [plasma membrane]

Stable Identifier

R-HSA-266067

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Dipeptidase 2-1, DPEP2_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Leishmania parasite growth and survival (Homo sapiens)
        
        Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        LTC4-CYSLTR mediated IL4 production (Homo sapiens)
        
        LTD4 is converted to LTE4 by DPEP1/2 (Homo sapiens)
        
        DPEP1,2,3 dimers [plasma membrane] (Homo sapiens)
        
        DPEP2 dimer [plasma membrane] (Homo sapiens)
        
        DPEP2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H4A9 DPEP2

Gene Names

DPEP2, UNQ284/PRO323

Chain

signal peptide:1-32, chain:33-463, propeptide:464-486

Reference Genes

BioGPS Gene:64174 DPEP2

COSMIC (genes):DPEP2 DPEP2

CTD Gene:64174 DPEP2

dbSNP Gene:64174 DPEP2

ENSEMBL:ENSG00000167261 DPEP2

ENSEMBL_homo_sapiens_GENE:ENSG00000167261.14 DPEP2

HGNC:23028 DPEP2

KEGG Gene (Homo sapiens):64174 DPEP2

Monarch:64174 DPEP2

NCBI Gene:64174 DPEP2

OMIM:609925 DPEP2

UCSC:Q9H4A9 DPEP2

Reference Transcript

RefSeq:NM_022355.3 DPEP2

Other Identifiers

11724979_a_at

16827546

219452_PM_at

219452_at

3696143

3696144

3696145

3696146

3696147

3696148

3696149

3696151

3696152

3696153

3696154

3696156

3696158

3696159

3696161

3696162

3696163

3696164

3696165

3696166

3696167

3696169

3696170

3696172

3696173

4003922

48510_at

64174

8002194

A_23_P118025

GE62071

GO:0003824

GO:0006508

GO:0006629

GO:0006691

GO:0006790

GO:0008233

GO:0008237

GO:0008238

GO:0016020

GO:0016787

GO:0016805

GO:0046872

GO:0070573

GO:0098552

GO:0140096

GO:1901749

HMNXSV003005038

HMNXSV003007189

HMNXSV003019575

HMNXSV003026475

ILMN_1689160

PH_hs_0026524

TC16001201.hg

g11641268_3p_at

Participates

as a component of

DPEP2 dimer [plasma membrane] (Homo sapiens)

Inferred To

Dmel\CG6154 [plasma membrane] (Drosophila melanogaster)

Homologues of DPEP2 [plasma membrane] (Drosophila melanogaster)

Homologues of DPEP2 [plasma membrane] (Schizosaccharomyces pombe)

DPEP2 [plasma membrane] (Bos taurus)

DPEP2 [plasma membrane] (Canis familiaris)

DPEP2 [plasma membrane] (Gallus gallus)

DPEP2 [plasma membrane] (Mus musculus)

DPEP2 [plasma membrane] (Rattus norvegicus)

DPEP2 [plasma membrane] (Schizosaccharomyces pombe)

DPEP2 [plasma membrane] (Sus scrofa)

CG5917 [plasma membrane] (Drosophila melanogaster)

Dmel\CG5282 [plasma membrane] (Drosophila melanogaster)

CG7198 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_071750.1

Guide to Pharmacology - Targets

1394

OpenTargets

ENSG00000167261

HPA

ENSG00000167261-DPEP2

GeneCards

Q9H4A9

Ensembl

ENST00000575203, ENSP00000459375, ENSP00000377430, ENST00000393847, ENSG00000167261, ENSP00000458977, ENST00000572888

PRO

Q9H4A9

Pharos - Targets

Q9H4A9

HMDB Protein

HMDBP09150