Reactome | DPEP2 [plasma membrane]

DPEP2 [plasma membrane]

Stable Identifier

R-HSA-266067

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Dipeptidase 2-1, DPEP2_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Leishmania parasite growth and survival (Homo sapiens)
        
        Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        LTC4-CYSLTR mediated IL4 production (Homo sapiens)
        
        LTD4 is converted to LTE4 by DPEP1/2 (Homo sapiens)
        
        DPEP1,2 dimers [plasma membrane] (Homo sapiens)
        
        DPEP2 dimer [plasma membrane] (Homo sapiens)
        
        DPEP2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H4A9 DPEP2

Gene Names

DPEP2, UNQ284/PRO323

Chain

signal peptide:1-32, chain:33-463, propeptide:464-486

Reference Genes

BioGPS Gene:64174 DPEP2

COSMIC (genes):DPEP2 DPEP2

CTD Gene:64174 DPEP2

dbSNP Gene:64174 DPEP2

ENSEMBL:ENSG00000167261 DPEP2

HGNC:23028 DPEP2

KEGG:hsa:64174 DPEP2

Monarch:64174 DPEP2

NCBI Gene:64174 DPEP2

OMIM:609925 DPEP2

UCSC:Q9H4A9 DPEP2

Reference Transcript

RefSeq:NM_022355.3 DPEP2

Other Identifiers

11724979_a_at

16827546

219452_PM_at

219452_at

3696143

3696144

3696145

3696146

3696147

3696148

3696149

3696150

3696151

3696152

3696153

3696154

3696155

3696156

3696157

3696158

3696159

3696160

3696161

3696162

3696163

3696164

3696165

3696166

3696167

3696169

3696170

3696172

3696173

4003922

48510_at

64174

8002194

A_23_P118025

GE62071

GO:0003824

GO:0006508

GO:0006629

GO:0006691

GO:0006790

GO:0008237

GO:0008238

GO:0016020

GO:0016787

GO:0016805

GO:0046872

GO:0070573

GO:0098552

GO:0140096

GO:1901749

HMNXSV003005038

HMNXSV003007189

HMNXSV003019575

HMNXSV003026475

ILMN_1689160

PH_hs_0026524

TC16001201.hg

g11641268_3p_at

Participates

as a component of

DPEP2 dimer [plasma membrane] (Homo sapiens)

Inferred To

Dmel\CG6154 [plasma membrane] (Drosophila melanogaster)

Homologues of DPEP2 [plasma membrane] (Drosophila melanogaster)

Homologues of DPEP2 [plasma membrane] (Schizosaccharomyces pombe)

DPEP2 [plasma membrane] (Bos taurus)

DPEP2 [plasma membrane] (Canis familiaris)

DPEP2 [plasma membrane] (Gallus gallus)

DPEP2 [plasma membrane] (Mus musculus)

DPEP2 [plasma membrane] (Rattus norvegicus)

DPEP2 [plasma membrane] (Schizosaccharomyces pombe)

DPEP2 [plasma membrane] (Sus scrofa)

CG5917 [plasma membrane] (Drosophila melanogaster)

Dmel\CG5282 [plasma membrane] (Drosophila melanogaster)

CG7198 [plasma membrane] (Drosophila melanogaster)

Cross References

Guide to Pharmacology - Targets

1394

ENSEMBL

ENSP00000459375, ENST00000572888, ENSG00000167261, ENSP00000377430, ENSP00000458977, ENST00000575203, ENST00000393847

OpenTargets

ENSG00000167261

GeneCards

DPEP2

HPA

ENSG00000167261-DPEP2

PRO

Q9H4A9

Pharos - Targets

Q9H4A9

GlyGen

Q9H4A9

HMDB Protein

HMDBP09150