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CACNA2D2(19-1150) [plasma membrane]
Stable Identifier
R-HSA-265749
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Voltage-gated Calcium Channel alpha-2/delta-2 subunit
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Adrenaline,noradrenaline inhibits insulin secretion (Homo sapiens)
L-type Calcium Channels close in pancreatic beta cells (Homo sapiens)
Voltage-gated Calcium Channels Type Cav1 (closed) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type 1.2 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type, 1.3 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channels Type Cav1 (open) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type 1.2 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type, 1.3 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Calcium Influx through Voltage-gated Calcium Channels (Homo sapiens)
Voltage-gated Calcium Channels (pancreatic beta cell) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type 1.2 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type, 1.3 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, P,Q-type 2.1 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, R-type 2.3 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Exocytosis of Insulin (Homo sapiens)
Voltage-gated Calcium Channels Type Cav1 (closed) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type 1.2 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type, 1.3 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
CACNA1D:CACNA2D2:CACNB2 (Cav1.3 channel) transports Ca2+ into the cytosol of an inner hair cell (Homo sapiens)
CACNA1D:CACNB2:CACA2D2 [plasma membrane] (Homo sapiens)
CACNA2D2(19-1150) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NY47 CACNA2D2
Gene Names
CACNA2D2, KIAA0558
Chain
signal peptide:1-18, chain:19-1150, chain:19-1001, chain:1002-1150
Reference Genes
BioGPS Gene:9254 CACNA2D2
COSMIC (genes):CACNA2D2 CACNA2D2
CTD Gene:9254 CACNA2D2
dbSNP Gene:9254 CACNA2D2
ENSEMBL:ENSG00000007402 CACNA2D2
HGNC:1400 CACNA2D2
KEGG:hsa:9254 CACNA2D2
Monarch:9254 CACNA2D2
NCBI Gene:9254 CACNA2D2
OMIM:607082 CACNA2D2
UCSC:Q9NY47 CACNA2D2
Reference Transcript
RefSeq:NM_006030.3 CACNA2D2
RefSeq:NM_001174051.2 CACNA2D2
RefSeq:NM_001291101.1 CACNA2D2
RefSeq:NM_001005505.2 CACNA2D2
Other Identifiers
11730116_s_at
11754210_a_at
16954507
204811_PM_s_at
204811_s_at
242806_PM_at
242806_at
2675316
2675317
2675318
2675319
2675320
2675321
2675322
2675324
2675325
2675326
2675327
2675328
2675329
2675330
2675331
2675332
2675333
2675334
2675335
2675337
2675338
2675339
2675340
2675341
2675342
2675343
2675344
2675346
2675347
2675348
2675349
2675350
2675351
2675352
2675353
2675354
2675355
2675356
2675357
2675364
2675397
2675409
2675410
2675411
2675412
2675413
2675442
37811_at
42478_at
8087691
9254
A_23_P346900
GE54350
GO:0005215
GO:0005245
GO:0005262
GO:0005886
GO:0005891
GO:0007528
GO:0016020
GO:0034330
GO:0034702
GO:0035265
GO:0040014
GO:0046622
GO:0046872
GO:0048787
GO:0048856
GO:0055001
GO:0055085
GO:0060024
GO:0070588
GO:0098696
GO:0098982
HMNXSV003039824
Hs.111806.0.A1_3p_at
ILMN_1711049
ILMN_2355274
PH_hs_0024498
PH_hs_0033088
TC03001433.hg
g5174402_3p_a_at
Participates
as a component of
CACNA1D:CACNB2:CACA2D2 [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, P,Q-type 2.1 [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type 1.2 [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, R-type 2.3 [plasma membrane] (Homo sapiens)
Voltage-gated Calcium Channel, L-type, 1.3 [plasma membrane] (Homo sapiens)
Other forms of this molecule
CACNA2D2(19-1001) [plasma membrane]
CACNA2D2(1002-1150) [plasma membrane]
CACNA2D2(19-1150) [extracellular region]
Inferred To
unc-36 [plasma membrane]
(Caenorhabditis elegans)
CACNA2D2(19-1150) [plasma membrane]
(Gallus gallus)
CACNA2D2(19-1150) [plasma membrane]
(Mus musculus)
CACNA2D2(19-1150) [plasma membrane]
(Rattus norvegicus)
Homologues of CACNA2D2(19-1150) [plasma membrane]
(Drosophila melanogaster)
Ca-Ma2d [plasma membrane]
(Drosophila melanogaster)
stj [plasma membrane]
(Drosophila melanogaster)
stol [plasma membrane]
(Drosophila melanogaster)
CACNA2D2 [plasma membrane]
(Bos taurus)
CACNA2D2 [plasma membrane]
(Canis familiaris)
CACNA2D2 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001278030.1
,
NP_001167522.1
,
NP_001005505.1
,
NP_006021.2
ENSEMBL
ENSP00000418081
,
ENST00000424201
,
ENST00000360963
,
ENST00000266039
,
ENSP00000354228
,
ENST00000479441
,
ENSP00000390329
,
ENSP00000266039
OpenTargets
ENSG00000007402
HPA
ENSG00000007402-CACNA2D2
ZINC - Substances
CA2D2_HUMAN
ZINC target
Q9NY47
PRO
Q9NY47
Pharos - Targets
Q9NY47
GlyGen
Q9NY47
ZINC - Predictions - Purchasable
CA2D2_HUMAN
HMDB Protein
HMDBP07485
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