Reactome | GGT5(1-387) [plasma membrane]

GGT5(1-387) [plasma membrane]

Stable Identifier

R-HSA-265313

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

GGT5 heavy chain, GGT5, GGT5_HUMAN, GGTLA1

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Leishmania parasite growth and survival (Homo sapiens)
        
        Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        LTC4-CYSLTR mediated IL4 production (Homo sapiens)
        
        GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Homo sapiens)
        
        GGT1, 5 dimers [plasma membrane] (Homo sapiens)
        
        GGT5 dimer [plasma membrane] (Homo sapiens)
        
        GGT5(1-387) [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P36269 GGT5

Gene Names

GGT5, GGTLA1

Chain

chain:1-387, chain:388-586

Reference Genes

BioGPS Gene:2687 GGT5

COSMIC (genes):GGT5 GGT5

CTD Gene:2687 GGT5

dbSNP Gene:2687 GGT5

ENSEMBL:ENSG00000099998 GGT5

HGNC:4260 GGT5

KEGG:hsa:2687 GGT5

Monarch:2687 GGT5

NCBI Gene:2687 GGT5

OMIM:137168 GGT5

UCSC:P36269 GGT5

Reference Transcript

Other Identifiers

11751636_a_at

11756254_a_at

16933140

205582_PM_s_at

205582_s_at

2687

38237_at

3901441

3901445

3939022

3939023

3939024

3939974

3939975

3952059

3952060

3952062

3953222

3953223

3955186

3955187

3955189

3955191

3955192

3955193

3955194

3955196

3955197

3955198

3955199

3955200

3955201

3955202

3955204

3955205

3955206

3955207

4038548

4038549

8074991

A_23_P166376

A_24_P297182

A_33_P3255304

GE56457

GO:0000048

GO:0002951

GO:0003824

GO:0005886

GO:0006508

GO:0006520

GO:0006575

GO:0006629

GO:0006631

GO:0006749

GO:0006750

GO:0006751

GO:0006790

GO:0006954

GO:0008233

GO:0016020

GO:0016740

GO:0016746

GO:0016787

GO:0019370

GO:0036374

GO:0103068

GO:0140096

GO:0140098

GO:1901750

HMNXSV003021425

ILMN_1749372

M64099_at

PH_hs_0020650

TC22000585.hg

g4758431_3p_a_at

Participates

as a component of

GGT5 dimer [plasma membrane] (Homo sapiens)

Other forms of this molecule

GGT5(388-586) [plasma membrane]

Inferred To

GGT5(1-387) [plasma membrane] (Bos taurus)

GGT5(1-387) [plasma membrane] (Caenorhabditis elegans)

GGT5(1-387) [plasma membrane] (Drosophila melanogaster)

GGT5(1-387) [plasma membrane] (Gallus gallus)

GGT5(1-387) [plasma membrane] (Mus musculus)

GGT5(1-387) [plasma membrane] (Rattus norvegicus)

GGT5(1-387) [plasma membrane] (Saccharomyces cerevisiae)

GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)

Homologues of GGT5(1-387) [plasma membrane] (Caenorhabditis elegans)

Homologues of GGT5(1-387) [plasma membrane] (Drosophila melanogaster)

Homologues of GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)

Cross References

ENSEMBL

ENSP00000330080, ENST00000263112, ENSP00000263112, ENSP00000381340, ENST00000398292, ENSG00000099998, ENST00000327365

OpenTargets

ENSG00000099998

IntEnz

3.4.19.13, 2.3.2.2

GeneCards

GGT5

HPA

ENSG00000099998-GGT5

PRO

P36269

Pharos - Targets

P36269

HMDB Protein

HMDBP09343

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q03426 MVK	1	MVK [cytosol] (R-HSA-191375)	0.527	2