Reactome | GGT5(388-586) [plasma membrane]

GGT5(388-586) [plasma membrane]

Stable Identifier

R-HSA-265312

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

GGT5 light chain, GGT5_HUMAN, GGTLA1

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Leishmania parasite growth and survival (Homo sapiens)
        
        Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        LTC4-CYSLTR mediated IL4 production (Homo sapiens)
        
        GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Homo sapiens)
        
        GGT1, 5 dimers [plasma membrane] (Homo sapiens)
        
        GGT5 dimer [plasma membrane] (Homo sapiens)
        
        GGT5(388-586) [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P36269 GGT5

Gene Names

GGT5, GGTLA1

Chain

chain:1-387, chain:388-586

Reference Genes

BioGPS Gene:2687 GGT5

COSMIC (genes):GGT5 GGT5

CTD Gene:2687 GGT5

dbSNP Gene:2687 GGT5

ENSEMBL:ENSG00000099998 GGT5

ENSEMBL:ENSG00000099998.19 GGT5

HGNC:4260 GGT5

KEGG Gene (Homo sapiens):2687 GGT5

Monarch:2687 GGT5

NCBI Gene:2687 GGT5

OMIM:137168 GGT5

UCSC:P36269 GGT5

Reference Transcript

Other Identifiers

11751636_a_at

11756254_a_at

16933140

205582_PM_s_at

205582_s_at

2687

38237_at

3901445

3939022

3939023

3939974

3939975

3952062

3955186

3955187

3955191

3955192

3955193

3955194

3955196

3955197

3955198

3955199

3955200

3955201

3955202

3955206

3955207

8074991

A_23_P166376

A_24_P297182

A_33_P3255304

GE56457

GO:0000048

GO:0002951

GO:0003824

GO:0005886

GO:0006508

GO:0006520

GO:0006575

GO:0006629

GO:0006631

GO:0006749

GO:0006750

GO:0006751

GO:0006790

GO:0006954

GO:0008233

GO:0016020

GO:0016740

GO:0016746

GO:0016787

GO:0019370

GO:0036374

GO:0102953

GO:0103068

GO:0140096

GO:1901750

HMNXSV003021425

ILMN_1749372

M64099_at

PH_hs_0020650

TC22000585.hg

g4758431_3p_a_at

Participates

as a component of

GGT5 dimer [plasma membrane] (Homo sapiens)

Other forms of this molecule

GGT5(1-387) [plasma membrane]

Inferred To

Dmel\CG1492 [plasma membrane] (Drosophila melanogaster)

Dmel\CG4829 [plasma membrane] (Drosophila melanogaster)

Ggt-1 [plasma membrane] (Drosophila melanogaster)

Homologues of GGT5(388-586) [plasma membrane] (Caenorhabditis elegans)

Homologues of GGT5(388-586) [plasma membrane] (Drosophila melanogaster)

Homologues of GGT5(388-586) [plasma membrane] (Schizosaccharomyces pombe)

GGT5(388-586) [plasma membrane] (Caenorhabditis elegans)

GGT5(388-586) [plasma membrane] (Gallus gallus)

GGT5(388-586) [plasma membrane] (Mus musculus)

GGT5(388-586) [plasma membrane] (Rattus norvegicus)

GGT5(388-586) [plasma membrane] (Saccharomyces cerevisiae)

GGT5(388-586) [plasma membrane] (Schizosaccharomyces pombe)

GGT5(388-586) [plasma membrane] (Sus scrofa)

GGT5 [plasma membrane] (Bos taurus)

ggt5 [plasma membrane] (Danio rerio)

ggt5 [plasma membrane] (Xenopus tropicalis)

Dmel\CG17636 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001289394.1, NP_001289393.1, NP_001093251.1, NP_004112.2, NP_001093252.1

OpenTargets

ENSG00000099998

IntEnz

3.4.19.13, 2.3.2.2

GeneCards

P36269

HPA

ENSG00000099998-GGT5

Ensembl

ENST00000263112, ENSP00000263112, ENSP00000381340, ENST00000398292, ENSG00000099998, ENSP00000330080, ENST00000327365

PRO

P36269

Pharos - Targets

P36269

HMDB Protein

HMDBP09343