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CPE [secretory granule membrane]
Stable Identifier
R-HSA-265204
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule membrane
Synonyms
Carboxypeptidase E
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Insulin processing (Homo sapiens)
Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) (Homo sapiens)
CPE:Zn2+ [secretory granule membrane] (Homo sapiens)
CPE [secretory granule membrane] (Homo sapiens)
Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) (Homo sapiens)
CPE:Zn2+ [secretory granule membrane] (Homo sapiens)
CPE [secretory granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P16870 CPE
Gene Names
CPE
Chain
signal peptide:1-25, propeptide:26-42, chain:43-476
Reference Genes
BioGPS Gene:1363 CPE
COSMIC (genes):CPE CPE
CTD Gene:1363 CPE
dbSNP Gene:1363 CPE
ENSEMBL:ENSG00000109472 CPE
ENSEMBL:ENSG00000109472.14 CPE
HGNC:2303 CPE
KEGG Gene (Homo sapiens):1363 CPE
Monarch:1363 CPE
NCBI Gene:1363 CPE
OMIM:114855 CPE
UCSC:P16870 CPE
Reference Transcript
RefSeq:NM_001873.3 CPE
Other Identifiers
11743576_at
11743577_s_at
1363
16972167
201116_PM_s_at
201116_s_at
201117_PM_s_at
201117_s_at
2750628
2750629
2750630
2750631
2750632
2750660
2750661
2750662
2750663
2750664
2750665
2750666
2750667
2750668
2750670
2750671
2750672
2750674
2750675
2750676
2750677
2750678
36606_at
8098204
A_23_P259442
GE510407
GO:0003214
GO:0003824
GO:0004180
GO:0004181
GO:0005515
GO:0005576
GO:0005615
GO:0005794
GO:0005886
GO:0006508
GO:0006518
GO:0007218
GO:0008233
GO:0008237
GO:0008270
GO:0016020
GO:0016055
GO:0016485
GO:0016787
GO:0023052
GO:0030070
GO:0030072
GO:0030133
GO:0030141
GO:0030658
GO:0030667
GO:0031410
GO:0033366
GO:0036211
GO:0042043
GO:0043226
GO:0046872
GO:0048856
GO:0050839
GO:0051604
GO:0070062
GO:0072657
GO:0140096
HMNXSV003010446
Hs.75360.0.A1_3p_a_at
ILMN_1731374
PH_hs_0004320
TC04000829.hg
X51405_at
g4503008_3p_a_at
g4503008_3p_x_at
Participates
as a component of
CPE:Zn2+ [secretory granule membrane] (Homo sapiens)
Cross References
RefSeq
NP_001864.1
Guide to Pharmacology - Targets
1595
OpenTargets
ENSG00000109472
HPA
ENSG00000109472-CPE
GeneCards
P16870
Ensembl
ENSP00000386104
,
ENST00000402744
,
ENSG00000109472
PRO
P16870
Pharos - Targets
P16870
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