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EXOC5 [cytosol]
Stable Identifier
R-HSA-265045
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Insulin processing (Homo sapiens)
Exocyst complex formation (Homo sapiens)
EXOC5 [cytosol] (Homo sapiens)
Exocyst Complex [plasma membrane] (Homo sapiens)
EXOC5 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane (Homo sapiens)
Exocyst Complex [plasma membrane] (Homo sapiens)
EXOC5 [cytosol] (Homo sapiens)
GGC-RALA:GTP:MYO1C:Exocyst [plasma membrane] (Homo sapiens)
Exocyst Complex [plasma membrane] (Homo sapiens)
EXOC5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00471 EXOC5
Gene Names
EXOC5, SEC10, SEC10L1
Chain
initiator methionine:1, chain:2-708
Reference Genes
BioGPS Gene:10640 EXOC5
COSMIC (genes):EXOC5 EXOC5
CTD Gene:10640 EXOC5
dbSNP Gene:10640 EXOC5
ENSEMBL:ENSG00000070367 EXOC5
HGNC:10696 EXOC5
KEGG Gene (Homo sapiens):10640 EXOC5
Monarch:10640 EXOC5
NCBI Gene:10640 EXOC5
OMIM:604469 EXOC5
UCSC:O00471 EXOC5
Reference Transcript
RefSeq:NM_006544.3 EXOC5
Other Identifiers
0000940025
10640
11719456_at
11719457_s_at
11719458_at
11719459_at
11749681_a_at
11749682_s_at
11757786_s_at
16793353
218748_s_at
222726_3p_s_at
222726_s_at
225084_at
228418_at
2729215
2729216
2729217
2729222
3566301
3566303
3566305
3566306
3566307
3566308
3566310
3566311
3566312
3566315
3566316
3566318
3566320
3566321
3566324
3566328
3566329
3566331
3566333
3566334
3566342
3566343
3566344
3566345
3566351
3566352
45744_at
57159_at
60837
7979367
8095333
88639_at
A0A0A0MSI8
A_23_P14464
A_24_P224219
A_24_P256830
A_32_P172755
AAB53388
AAH41126
AK312523
BAG35422
BC041126
CCDS45111
CH471061
EAW80699
ENSG00000070367
ENSP00000484855
ENST00000621441
ENST00000621441.4
EntrezGene:10640
EntrezGene:EXOC5
EXOC5
EXOC5-211
F8W9B8
G3V377
G3V4Z7
g5730036_3p_a_at
GE78968
GO:0000145
GO:0001736
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005829
GO:0006810
GO:0006887
GO:0006892
GO:0006893
GO:0008150
GO:0008219
GO:0015031
GO:0016192
GO:0017160
GO:0019899
GO:0022607
GO:0030496
GO:0032991
GO:0047485
GO:0048278
GO:0048856
GO:0072659
GO:1904019
GO:1905515
HGNC:10696
HPA060837
Hs.279947.0.S2_3p_s_at
Hs.29494.1.S1_3p_at
Hs.29494.2.S1_3p_at
Hs.29494.2.S1_3p_x_at
ILMN_1788625
IPR009976
IPR033960
MIM:604469
NM_006544
NP_006535
PF07393
PH_hs_0029885
TC14001170.hg
U85946
U85946_at
UPI0000047E53
XM_005267272
XP_005267329
Participant Of
hasComponent
Exocyst Complex [plasma membrane]
input
Exocyst complex formation
Other forms of this molecule
EXOC5 [cytosol]
Inferred To
EXOC5 [cytosol] (Bos taurus)
EXOC5 [cytosol] (Caenorhabditis elegans)
EXOC5 [cytosol] (Canis familiaris)
EXOC5 [cytosol] (Danio rerio)
EXOC5 [cytosol] (Dictyostelium discoideum)
EXOC5 [cytosol] (Drosophila melanogaster)
EXOC5 [cytosol] (Gallus gallus)
EXOC5 [cytosol] (Mus musculus)
EXOC5 [cytosol] (Rattus norvegicus)
EXOC5 [cytosol] (Saccharomyces cerevisiae)
EXOC5 [cytosol] (Schizosaccharomyces pombe)
EXOC5 [cytosol] (Sus scrofa)
EXOC5 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_006535.1
OpenTargets
ENSG00000070367
GeneCards
O00471
PRO
O00471
Interactors (49)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8TAG9 EXOC6
2
EXOC6 [plasma membrane]
(R-HSA-265041)
EXOC6 [cytosol]
(R-HSA-5623384)
0.767
6
UniProt:Q13882 PTK6
5
PTK6 [cytosol]
(R-HSA-8848000)
p-Y342-PTK6 [cytosol]
(R-HSA-8848007)
p-Y351-PTK6 [cytosol]
(R-HSA-8857570)
p-Y342,Y447-PTK6 [cytosol]
(R-HSA-8849103)
p-Y342-PTK6 [nucleoplasm]
(R-HSA-8848937)
0.696
5
UniProt:P00973-2 OAS1
0.696
5
UniProt:Q05D60 DEUP1
0.696
12
UniProt:P61106 RAB14
7
GGC-RAB14 [recycling endosome membrane]
(R-HSA-8876593)
GGC-RAB14 [cytoplasmic vesicle membrane]
(R-HSA-1445086)
GGC-RAB14 [cytosol]
(R-HSA-8873763)
RAB14 [cytosol]
(R-HSA-8873701)
RAB14 [early endosome membrane]
(R-HSA-8871372)
RAB14 [plasma membrane]
(R-HSA-6806438)
RAB14 [tertiary granule membrane]
(R-HSA-6800407)
0.696
5
UniProt:P43360 MAGA6
0.696
5
UniProt:P20338 RAB4A
5
GGC-RAB4A [cytosol]
(R-HSA-8874045)
GGC-RAB4A [cytoplasmic vesicle membrane]
(R-HSA-1458526)
RAB4A [cytosol]
(R-HSA-8873709)
RAB4A [early endosome membrane]
(R-HSA-8871356)
GGC-RAB4A [recycling endosome membrane]
(R-HSA-8875666)
0.696
5
UniProt:P61018 RAB4B
5
RAB4B [cytosol]
(R-HSA-8873680)
GGC-RAB4B [cytosol]
(R-HSA-8874049)
RAB4B [plasma membrane]
(R-HSA-6804989)
RAB4B [secretory granule membrane]
(R-HSA-6804976)
GGC-RAB4B [recycling endosome membrane]
(R-HSA-8875675)
0.696
5
UniProt:Q9Y2D4 EXC6B
0.695
8
UniProt:O14787 TNPO2
0.666
4
UniProt:Q8N3L3 TXLNB
0.666
4
UniProt:O60645 EXOC3
2
EXOC3 [secretory granule membrane]
(R-HSA-2872286)
EXOC3 [cytosol]
(R-HSA-5623379)
0.638
3
UniProt:Q8IYI6 EXOC8
2
EXOC8 [cytosol]
(R-HSA-5623388)
EXOC8 [plasma membrane]
(R-HSA-264948)
0.638
4
UniProt:Q6PF05-3 TTC23L
0.556
3
UniProt:P00973 OAS1
1
OAS1 [cytosol]
(R-HSA-947486)
0.556
3
UniProt:Q9ULZ3 PYCARD
4
PYCARD [extracellular region]
(R-HSA-6806196)
PYCARD [azurophil granule lumen]
(R-HSA-6798768)
PYCARD [secretory granule lumen]
(R-HSA-6800957)
PYCARD [cytosol]
(R-HSA-561191)
0.556
5
UniProt:P83876 TXNL4A
1
TXNL4A [nucleoplasm]
(R-HSA-71875)
0.556
3
UniProt:Q96E40 SACA9
0.556
3
UniProt:Q9BQD3 KXDL1
0.556
3
UniProt:Q8N4P3 MESH1
0.556
3
UniProt:A0A0S2Z528 A0A0S2Z528
0.556
3
UniProt:Q5PSV4 BRM1L
0.556
3
UniProt:Q6FHV6 Q6FHV6
0.556
3
UniProt:Q96NE9 FRMD6
0.556
3
UniProt:O14964 HGS
2
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
HGS [cytosol]
(R-HSA-182954)
0.556
3
UniProt:Q68D86 C102B
0.556
3
IntAct:EBI-16430217 CCSB ISOFORM ID
0.556
3
UniProt:A0AVN2 A0AVN2
0.556
3
UniProt:A0A0S2Z4Q4 A0A0S2Z4Q4
0.556
3
UniProt:Q3B7T1-5 EDRF1
0.556
3
UniProt:Q99728 BARD1
2
BARD1 [nucleoplasm]
(R-HSA-5659775)
p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-5659846)
0.556
3
UniProt:P46459 NSF
1
NSF [cytosol]
(R-HSA-264471)
0.508
2
UniProt:Q9UPT5 EXOC7
2
EXOC7 [plasma membrane]
(R-HSA-2872288)
EXOC7 [cytosol]
(R-HSA-5623386)
0.508
3
UniProt:Q15051 IQCB1
1
IQCB1 [cytosol]
(R-HSA-5626648)
0.508
2
UniProt:P61006 RAB8A
6
RAB8A [recycling endosome membrane]
(R-HSA-8854145)
GGC-RAB8A [cytoplasmic vesicle membrane]
(R-HSA-1445093)
GGC-RAB8A [trans-Golgi network membrane]
(R-HSA-8876082)
GGC-RAB8A [cytosol]
(R-HSA-8874063)
RAB8A [cytosol]
(R-HSA-5623399)
RAB8A [Golgi membrane]
(R-HSA-2562535)
0.508
2
UniProt:O15014 ZN609
0.508
2
UniProt:Q13586 STIM1
1
STIM1 [endoplasmic reticulum membrane]
(R-HSA-434675)
0.508
2
UniProt:Q96KP1 EXOC2
2
EXOC2 [plasma membrane]
(R-HSA-264887)
EXOC2 [cytosol]
(R-HSA-5623376)
0.508
2
UniProt:Q9NV70 EXOC1
2
EXOC1 [cytosol]
(R-HSA-5623375)
EXOC1 [plasma membrane]
(R-HSA-2872284)
0.508
3
UniProt:Q96A65 EXOC4
2
EXOC4 [plasma membrane]
(R-HSA-264989)
EXOC4 [cytosol]
(R-HSA-5623381)
0.508
3
UniProt:Q6ZMS7 ZN783
0.488
2
UniProt:Q9NWB7 IFT57
2
IFT57 [cilium]
(R-HSA-5610389)
IFT57 [ciliary tip]
(R-HSA-5625363)
0.488
2
UniProt:Q8TAB5 CA216
0.488
2
UniProt:Q96FV9 THOC1
1
THOC1 [nucleoplasm]
(R-HSA-8849130)
0.488
2
UniProt:P53674 CRBB1
0.488
2
UniProt:P43357 MAGA3
0.488
2
UniProt:Q9BVG8-5 KIFC3
0.488
4
UniProt:O75604 USP2
2
USP2 [nucleoplasm]
(R-HSA-5689946)
USP2 [cytosol]
(R-HSA-5212661)
0.488
2
UniProt:P02671-2 FGA
0.488
2
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