Reactome | SSR4 [endoplasmic reticulum membrane]

SSR4 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-265026

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Trap delta

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P51571 SSR4

Gene Names

SSR4, TRAPD

Chain

signal peptide:1-23, chain:24-173

Reference Genes

BioGPS Gene:6748 SSR4

COSMIC (genes):SSR4 SSR4

CTD Gene:6748 SSR4

dbSNP Gene:6748 SSR4

ENSEMBL:ENSG00000180879 SSR4

ENSEMBL_homo_sapiens_GENE:ENSG00000180879.14 SSR4

HGNC:11326 SSR4

KEGG Gene (Homo sapiens):6748 SSR4

Monarch:6748 SSR4

NCBI Gene:6748 SSR4

OMIM:300090 SSR4

UCSC:P51571 SSR4

Reference Transcript

Other Identifiers

11754950_a_at

201004_PM_at

201004_at

38635_at

3995976

3995977

3995978

3995979

3995980

3995981

3995982

3995984

3995992

3995994

3995996

3995999

3996003

3996004

6748

8170775

A_14_P114203

A_14_P128626

A_23_P259172

GE60428

GO:0005576

GO:0005615

GO:0005783

GO:0005784

GO:0005789

GO:0012505

GO:0016020

GO:0043226

GO:0070062

HMNXSV003025848

ILMN_1680403

PH_hs_0019492

TC0X001928.hg

Z69043_s_at

g5454089_3p_at

Participates

as a component of

TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_011529488.1, NP_006271.1, NP_001191455.1, XP_011529489.1

OpenTargets

ENSG00000180879

GeneCards

P51571

HPA

ENSG00000180879-SSR4

Ensembl

ENSP00000317331, ENSP00000359104, ENST00000370087, ENSP00000359103, ENST00000370086, ENST00000320857, ENSG00000180879

PRO

P51571

Pharos - Targets

P51571

Orphanet

22581

HMDB Protein

HMDBP08011

PDB

8B6L

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	10
UniProt:P04578 env	7	Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211)	0.462	2

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