Reactome | SSR4 [endoplasmic reticulum membrane]

SSR4 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-265026

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Trap delta

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P51571 SSR4

Gene Names

SSR4, TRAPD

Chain

signal peptide:1-23, chain:24-173

Reference Genes

BioGPS Gene:6748 SSR4

COSMIC (genes):SSR4 SSR4

CTD Gene:6748 SSR4

dbSNP Gene:6748 SSR4

ENSEMBL:ENSG00000180879 SSR4

HGNC:11326 SSR4

KEGG:hsa:6748 SSR4

Monarch:6748 SSR4

NCBI Gene:6748 SSR4

OMIM:300090 SSR4

UCSC:P51571 SSR4

Reference Transcript

Other Identifiers

11754950_a_at

17108181

201004_PM_at

201004_at

38635_at

3995976

3995977

3995978

3995979

3995980

3995981

3995982

3995983

3995984

3995985

3995986

3995987

3995988

3995989

3995990

3995991

3995992

3995993

3995994

3995995

3995996

3995997

3995998

3995999

3996000

3996001

3996002

3996003

3996004

6748

8170775

A_14_P114203

A_14_P128626

A_23_P259172

GE60428

GO:0005783

GO:0005784

GO:0005789

GO:0012505

GO:0016020

GO:0043226

GO:0070062

HMNXSV003025848

ILMN_1680403

PH_hs_0019492

TC0X000757.hg

TC0X001928.hg

Z69043_s_at

g5454089_3p_at

Participates

as a component of

TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSP00000359104, ENSG00000180879, ENST00000370087, ENSP00000359103, ENST00000370086, ENST00000320857, ENSP00000317331

OpenTargets

ENSG00000180879

GeneCards

SSR4

HPA

ENSG00000180879-SSR4

PRO

P51571

Pharos - Targets

P51571

GlyGen

P51571

Orphanet

SSR4

HMDB Protein

HMDBP08011

PDB

8B6L

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	10
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	2

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