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SSR3 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-264973
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Trap gamma
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)
cleaved polypeptide:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)
SSR3 [endoplasmic reticulum membrane] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)
SSR3 [endoplasmic reticulum membrane] (Homo sapiens)
Signal-containing nascent peptide translocates to endoplasmic reticulum (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)
SSR3 [endoplasmic reticulum membrane] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)
SSR3 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UNL2 SSR3
Gene Names
SSR3, TRAPG
Chain
chain:1-185
Reference Genes
BioGPS Gene:6747 SSR3
COSMIC (genes):SSR3 SSR3
CTD Gene:6747 SSR3
dbSNP Gene:6747 SSR3
ENSEMBL:ENSG00000114850 SSR3
ENSEMBL_homo_sapiens_GENE:ENSG00000114850.7 SSR3
HGNC:11325 SSR3
KEGG Gene (Homo sapiens):6747 SSR3
Monarch:6747 SSR3
NCBI Gene:6747 SSR3
OMIM:606213 SSR3
UCSC:Q9UNL2 SSR3
Reference Transcript
RefSeq:NM_001308204.1 SSR3
RefSeq:NM_001308205.1 SSR3
RefSeq:NM_001308197.1 SSR3
RefSeq:NM_007107.4 SSR3
Other Identifiers
11734068_a_at
11734069_s_at
11734070_x_at
11753962_a_at
16960775
217790_PM_s_at
217790_s_at
222411_PM_s_at
222411_s_at
222412_PM_s_at
222412_s_at
2702151
2702153
2702155
2702156
2702157
2702158
2702159
2702160
2702161
2702165
2702168
2702171
2702172
2702173
60933_at
6747
67710_at
8091648
A_23_P155229
A_24_P319942
GE58436
GO:0005515
GO:0005783
GO:0005789
GO:0006614
GO:0006886
GO:0016020
GO:0043226
HMNXSV003009197
Hs.28707.0.S1_3p_a_at
Hs.28707.0.S2_3p_x_at
ILMN_1806906
PH_hs_0002508
TC03001933.hg
g6005883_3p_a_at
Participates
as a component of
TRAP Complex [endoplasmic reticulum membrane] (Homo sapiens)
Cross References
RefSeq
NP_009038.1
,
NP_001295133.1
,
NP_001295134.1
,
NP_001295126.1
OpenTargets
ENSG00000114850
GeneCards
Q9UNL2
HPA
ENSG00000114850-SSR3
Ensembl
ENSG00000114850
,
ENSP00000265044
,
ENSP00000420641
,
ENST00000265044
,
ENST00000467789
PRO
Q9UNL2
Pharos - Targets
Q9UNL2
HMDB Protein
HMDBP08012
PDB
8B6L
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27824 CANX
2
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
8
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