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SRPR [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-264970
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
SRP Receptor subunit alpha
Icon
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
IRE1alpha activates chaperones (Homo sapiens)
XBP1(S) activates chaperone genes (Homo sapiens)
Expression of SRPR (SRP Receptor subunit alpha) (Homo sapiens)
SRPR [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Signal-containing nascent peptide translocates to endoplasmic reticulum (Homo sapiens)
SRP receptor [endoplasmic reticulum membrane] (Homo sapiens)
SRPR [endoplasmic reticulum membrane] (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP receptor [endoplasmic reticulum membrane] (Homo sapiens)
SRPR [endoplasmic reticulum membrane] (Homo sapiens)
The SRP receptor binds the SRP:nascent peptide:ribosome complex (Homo sapiens)
SRP receptor [endoplasmic reticulum membrane] (Homo sapiens)
SRPR [endoplasmic reticulum membrane] (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP receptor [endoplasmic reticulum membrane] (Homo sapiens)
SRPR [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08240 SRPRA
Gene Names
SRPRA, SRPR
Chain
chain:1-638
Reference Genes
BioGPS Gene:6734 SRPRA
COSMIC (genes):SRPRA SRPRA
CTD Gene:6734 SRPRA
dbSNP Gene:6734 SRPRA
ENSEMBL:ENSG00000182934 SRPR
ENSEMBL_homo_sapiens_GENE:ENSG00000182934.12 SRPRA
HGNC:11307 SRPRA
KEGG Gene (Homo sapiens):6734 SRPRA
Monarch:6734 SRPRA
NCBI Gene:6734 SRPRA
OMIM:182180 SRPRA
UCSC:P08240 SRPRA
Reference Transcript
RefSeq:NM_003139.3 SRPRA
RefSeq:NM_001177842.1 SRPRA
Other Identifiers
11715471_a_at
11715472_a_at
11715473_at
11748071_a_at
11758316_s_at
16745922
200917_PM_s_at
200917_s_at
200918_PM_s_at
200918_s_at
3396918
3396919
3396920
3396921
3396922
3396923
3396925
3396926
3396927
3396930
3396931
3396933
3396934
3396935
3396936
3396938
3396939
3396940
3396942
3396943
3396945
3396947
3396950
3396951
36679_at
6734
7952557
A_23_P86943
A_24_P321369
GE59679
GO:0000166
GO:0003723
GO:0003824
GO:0003924
GO:0005047
GO:0005525
GO:0005576
GO:0005615
GO:0005783
GO:0005785
GO:0005789
GO:0006613
GO:0006614
GO:0006617
GO:0006886
GO:0016020
GO:0016787
GO:0016887
GO:0043226
GO:0045047
GO:0065003
GO:0070062
GO:0140657
HMNXSV003032977
Hs.75730.0.S1_3p_a_at
ILMN_1785660
PH_hs_0025939
TC11002431.hg
X06272_at
g4507222_3p_a_at
Participates
as an output of
Expression of SRPR (SRP Receptor subunit alpha) (Homo sapiens)
as a component of
SRP receptor [endoplasmic reticulum membrane] (Homo sapiens)
Cross References
RefSeq
NP_001171313.1
,
NP_003130.2
OpenTargets
ENSG00000182934
HPA
ENSG00000182934-SRPRA
GeneCards
P08240
Ensembl
ENSG00000182934
,
ENST00000532259
,
ENST00000332118
,
ENSP00000435508
,
ENSP00000328023
PRO
P08240
Pharos - Targets
P08240
HMDB Protein
HMDBP08586
PDB
7NFX
,
2FH5
,
5L3Q
,
2GO5
,
6Y32
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y5M8 SRPRB
1
SRPRB [endoplasmic reticulum membrane]
(R-HSA-265002)
0.725
5
UniProt:Q9NUM3 S39A9
0.527
2
UniProt:Q6UWB1 IL27RA
4
IL27RA [plasma membrane]
(R-HSA-448478)
p-Y611-IL27RA [plasma membrane]
(R-HSA-8950330)
sIL27RA [extracellular region]
(R-HSA-8950454)
sIL27RA [cytoplasm]
(R-HSA-8950653)
0.527
2
UniProt:P0DTD8 NS7B
0.527
2
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