Caspase-mediated cleavage of cytoskeletal proteins

Stable Identifier
R-HSA-264870
Type
Pathway
Species
Homo sapiens
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Caspase-mediated cleavage of cytoskeletal proteins
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Caspase-mediated cleavage of a number of proteins in the cortical actin network ( ) microfilament system and others involved in maintenance of the cytoskeletal architecture (vimentin, or Gas2 and plectin) may directly contribute to apoptotic changes in cell shape.

Literature References
PubMed ID Title Journal Year
12655297 Many cuts to ruin: a comprehensive update of caspase substrates

Fischer, U, Janicke, RU, Schulze-Osthoff, K

Cell Death Differ 2003
17254298 SVM-based prediction of caspase substrate cleavage sites

Wee, LJ, Tan, TW, Ranganathan, S

BMC Bioinformatics 2006
17599937 CASVM: web server for SVM-based prediction of caspase substrates cleavage sites

Wee, LJ, Tan, TW, Ranganathan, S

Bioinformatics 2007
Participants
Events
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Orthologous Events
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Caspase-mediated cleavage of cytoskeletal proteins (Drosophila melanogaster)
Caspase-mediated cleavage of cytoskeletal proteins (Gallus gallus)
Caspase-mediated cleavage of cytoskeletal proteins (Mus musculus)
Caspase-mediated cleavage of cytoskeletal proteins (Rattus norvegicus)
Caspase-mediated cleavage of cytoskeletal proteins (Sus scrofa)
Caspase-mediated cleavage of cytoskeletal proteins (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Schulze-Osthoff, K  (2007-09-03)
Reviewed
Ranganathan, S  (2008-06-11)
Created
Matthews, L  (2008-04-14)
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