Caspases initiate the destruction of the nucleus cleavage of lamins leads to disassembly of the nuclear lamina. Lamin A is cleaved by active caspase 6 (Orth et al., 1996).
Orth, K, Chinnaiyan, AM, Garg, M, Froelich, CJ, Dixit, VM
Lazebnik, YA, Takahashi, A, Poirier, GG, Kaufmann, SH, Earnshaw, WC
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