Cho is acetylated to AcCho by CHAT

Stable Identifier
R-HSA-264622
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Synthesis of o-acetylcholine
Locations in the PathwayBrowser
General
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In the cytosol, choline O-acetyltransferase (CHAT) acetylates choline (Cho) to produce acetylcholine (AcCho) (Toussaint 1992).

AcCho is synthesised in the cytoplasm of cholinergic neurons from acetyl-CoA and Cho by CHAT enzyme.

Literature References
PubMed ID Title Journal Year
1339386 Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions

Toussaint, JL

Genomics 1992
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
choline O-acetyltransferase activity of CHAT [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
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