AJUBA binds centrosome-associated AURKA

Stable Identifier
R-HSA-2574845
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
AJUBA binds centrosome-associated AURKA
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
AJUBA, a LIM domain-containing protein, binds centrosome-associated AURKA (Aurora A kinase) through interaction of LIM-2 and LIM-3 domains of AJUBA with the N-terminus of AURKA (Hirota et al. 2003).
Literature References
PubMed ID Title Journal Year
13678582 Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

Hirota, T, Kunitoku, N, Sasayama, T, Marumoto, T, Zhang, D, Nitta, M, Hatakeyama, K, Saya, H

Cell 2003
Participants
Input
Output
Participates
as an event of
Orthologous Events
AJUBA binds centrosome-associated AURKA (Bos taurus)
AJUBA binds centrosome-associated AURKA (Canis familiaris)
AJUBA binds centrosome-associated AURKA (Gallus gallus)
AJUBA binds centrosome-associated AURKA (Mus musculus)
AJUBA binds centrosome-associated AURKA (Rattus norvegicus)
AJUBA binds centrosome-associated AURKA (Sus scrofa)
AJUBA binds centrosome-associated AURKA (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2013-01-29)
Reviewed
Bruinsma, W  (2013-08-21)
Created
Orlic-Milacic, M  (2012-11-12)
Cite Us!