AJUBA binds centrosome-associated AURKA

Stable Identifier
R-HSA-2574845
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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AJUBA binds centrosome-associated AURKA
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AJUBA, a LIM domain-containing protein, binds centrosome-associated AURKA (Aurora A kinase) through interaction of LIM-2 and LIM-3 domains of AJUBA with the N-terminus of AURKA (Hirota et al. 2003).

Literature References
PubMed ID Title Journal Year
13678582 Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

Hirota, T, Hatakeyama, K, Nitta, M, Sasayama, T, Saya, H, Kunitoku, N, Zhang, D, Marumoto, T

Cell 2003
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Orthologous Events
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AJUBA binds centrosome-associated AURKA (Mus musculus)
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AJUBA binds centrosome-associated AURKA (Sus scrofa)
AJUBA binds centrosome-associated AURKA (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2013-01-29)
Reviewed
Bruinsma, W  (2013-08-21)
Created
Orlic-Milacic, M  (2012-11-12)
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