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GLRX5 [mitochondrial matrix]
Stable Identifier
R-HSA-2564761
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Glutaredoxin-related protein 5, mitochondrial, GLRX5_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Mitochondrial iron-sulfur cluster biogenesis (Homo sapiens)
Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Homo sapiens)
GLRX5 [mitochondrial matrix] (Homo sapiens)
GLRX5:2Fe-2S [mitochondrial matrix] (Homo sapiens)
GLRX5 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86SX6 GLRX5
Gene Names
GLRX5, C14orf87
Chain
transit peptide:1-31, chain:32-157
Reference Genes
BioGPS Gene:51218 GLRX5
COSMIC (genes):GLRX5 GLRX5
CTD Gene:51218 GLRX5
dbSNP Gene:51218 GLRX5
ENSEMBL:ENSG00000182512 GLRX5
ENSEMBL_homo_sapiens_GENE:ENSG00000182512.5 GLRX5
HGNC:20134 GLRX5
KEGG Gene (Homo sapiens):51218 GLRX5
Monarch:51218 GLRX5
NCBI Gene:51218 GLRX5
OMIM:609588 GLRX5
UCSC:Q86SX6 GLRX5
Reference Transcript
RefSeq:NM_016417.2 GLRX5
Other Identifiers
11721673_at
11721674_s_at
11721675_x_at
221932_PM_s_at
221932_s_at
3550095
3550096
3550097
3550105
3550106
3550107
3989238
51218
59721_at
65171_at
7976515
8169709
A_14_P100150
A_23_P65370
GE82122
GE86641
GO:0005515
GO:0005739
GO:0005759
GO:0005829
GO:0006790
GO:0006879
GO:0016226
GO:0030097
GO:0030154
GO:0030425
GO:0043025
GO:0043226
GO:0044571
GO:0045454
GO:0046872
GO:0048856
GO:0051536
GO:0051537
GO:0051604
GO:0055065
GO:0106034
GO:0106035
GO:1990229
HMNXSV003055542
Hs.13201.1.S1_3p_a_at
ILMN_1796165
PH_hs_0015296
PH_hs_0038812
RNA96181|RNS_1263_60
TC14000593.hg
Participates
as an output of
Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Homo sapiens)
as a component of
GLRX5:2Fe-2S [mitochondrial matrix] (Homo sapiens)
Inferred To
Grx5 [mitochondrial matrix]
(Drosophila melanogaster)
Glrx5 [mitochondrial matrix]
(Rattus norvegicus)
glrx5 [mitochondrial matrix]
(Xenopus tropicalis)
GLRX5 [mitochondrial matrix]
(Bos taurus)
GLRX5 [mitochondrial matrix]
(Canis familiaris)
GLRX5 [mitochondrial matrix]
(Danio rerio)
GLRX5 [mitochondrial matrix]
(Dictyostelium discoideum)
GLRX5 [mitochondrial matrix]
(Gallus gallus)
GLRX5 [mitochondrial matrix]
(Mus musculus)
GLRX5 [mitochondrial matrix]
(Saccharomyces cerevisiae)
GLRX5 [mitochondrial matrix]
(Schizosaccharomyces pombe)
GLRX5 [mitochondrial matrix]
(Sus scrofa)
glrx-5 [mitochondrial matrix]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_057501.2
OpenTargets
ENSG00000182512
GeneCards
Q86SX6
HPA
ENSG00000182512-GLRX5
Ensembl
ENST00000331334
,
ENSG00000182512
,
ENSP00000328570
PRO
Q86SX6
Pharos - Targets
Q86SX6
Orphanet
17878
PDB
2WUL
,
2MMZ
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q53S33 BOLA3
0.817
13
UniProt:Q8IWL3 HSCB
5
HSCB [mitochondrial matrix]
(R-HSA-1299438)
HSCB(1-30) [mitochondrial matrix]
(R-HSA-8986120)
HSCB(1-235) [mitochondrial inner membrane]
(R-HSA-1299443)
HSCB [mitochondrial inner membrane]
(R-HSA-1299447)
HSCB(1-235) [mitochondrial intermembrane space]
(R-HSA-1299456)
0.623
3
ChEBI:49601 FE2S2 IRON-SULFUR CLUSTER
0.558
2
UniProt:Q9Y3E2 BOLA1
0.527
6
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