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TPX2
Stable Identifier
R-HSA-2564700
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Targeting protein for Xklp2, DIL2, HCA519, C20orf1, C20orf2
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Activity through Phosphorylation (Homo sapiens)
AURKA phosphorylates TP53 (Homo sapiens)
p-T288-AURKA:TPX2 [nucleoplasm] (Homo sapiens)
TPX2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULW0 TPX2
Gene Names
TPX2, C20orf1, C20orf2, DIL2, HCA519
Chain
chain:1-747
Reference Genes
BioGPS Gene:22974 TPX2
COSMIC (genes):TPX2 TPX2
CTD Gene:22974 TPX2
dbSNP Gene:22974 TPX2
ENSEMBL:ENSG00000088325 TPX2
HGNC:1249 TPX2
KEGG Gene (Homo sapiens):hsa:22974 TPX2
Monarch:22974 TPX2
NCBI Gene:22974 TPX2
OMIM:605917 TPX2
UCSC:Q9ULW0 TPX2
Reference Transcript
RefSeq:NM_012112.4 TPX2
RefSeq:XM_011528697.2 TPX2
RefSeq:XM_011528699.2 TPX2
Other Identifiers
0003390500
11750598_s_at
16912379
1OL5
210052_s_at
22974
3385724
3881448
3881451
3881454
3881455
3881457
3881458
3881459
3881462
3881463
3881464
3881467
3881468
3881470
3881472
3881476
3881477
3881478
3881479
3881482
3881483
3881487
3881488
3881489
3881490
3881491
3881492
3881493
39109_at
3E5A
3HA6
45574_g_at
4C3P
5487
5LXM
8061579
A_23_P68610
CCDS13190
ENSG00000088325
ENSP00000300403
ENSP00000341145
ENST00000300403
ENST00000340513
EntrezGene:22974
g6073830_3p_a_at
GE53669
GO:0000278
GO:0000922
GO:0005515
GO:0005524
GO:0005525
GO:0005634
GO:0005654
GO:0005737
GO:0005819
GO:0005829
GO:0005856
GO:0005874
GO:0006915
GO:0007049
GO:0008283
GO:0010389
GO:0015630
GO:0019901
GO:0032147
GO:0043203
GO:0051301
GO:0060236
GO:0061676
GO:0072686
GO:0090307
GO:1901796
HGNC:1249
HPA005487
Hs.244580
ILMN_1792494
ILMN_1796949
MIM:605917
NM_012112
NP_036244
PF06886
PF09041
PF12214
PH_hs_0000972
Q643R0
TC20000198.hg
TPX2
TPX2-201
TPX2-202
uc002wwp.2
uc010gdv.2
UPI00000015BB
UPI0000071EB5
XM_011528697
XM_011528699
XM_011528700
XP_011526999
XP_011527001
XP_011527002
Participant Of
hasComponent
p-T288-AURKA:TPX2 [nucleoplasm]
Other forms of this molecule
TPX2 [cytosol]
Inferred To
TPX2 [nucleoplasm] (Bos taurus)
TPX2 [nucleoplasm] (Canis familiaris)
TPX2 [nucleoplasm] (Danio rerio)
TPX2 [nucleoplasm] (Mus musculus)
TPX2 [nucleoplasm] (Rattus norvegicus)
TPX2 [nucleoplasm] (Sus scrofa)
TPX2 [nucleoplasm] (Xenopus tropicalis)
Homologues of TPX2 [nucleoplasm] (Canis familiaris)
Homologues of TPX2 [nucleoplasm] (Danio rerio)
Homologues of TPX2 [nucleoplasm] (Sus scrofa)
Cross References
RefSeq
XP_011527001.1
,
NP_036244.2
,
XP_011526999.1
GeneCards
Q9ULW0
DOCK Blaster
3E5A
,
5LXM
,
1OL5
,
3HA6
,
4C3P
PRO
Q9ULW0
PDB
1OL5
,
4C3P
,
3E5A
,
5LXM
,
3HA6
,
6BJC
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14965 AURKA
6
AURKA [nucleoplasm]
(R-HSA-4655443)
SUMO1-K258-AURKA [cytosol]
(R-HSA-4655367)
p-T288-AURKA [nucleoplasm]
(R-HSA-6805089)
PolyUb-AURKA [cytosol]
(R-HSA-8854040)
AURKA [cytosol]
(R-HSA-174254)
p-T288-AURKA [cytosol]
(R-HSA-2574832)
0.806
7
UniProt:O75330 HMMR
2
HMMR [cytosol]
(R-HSA-8861624)
HMMR [plasma membrane]
(R-HSA-2160885)
0.499
5
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