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What is Reactome ?
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p-S177-OPTN [nucleoplasm]
Stable Identifier
R-HSA-2562595
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
p-S177-Optineurin
Locations in the PathwayBrowser for interactor UniProt:Q96EF9 ZHX1R
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
Regulation of PLK1 Activity at G2/M Transition (Homo sapiens)
Myosin phosphatase dephosphorylates PLK1 (Homo sapiens)
p-S177-OPTN [nucleoplasm] (Homo sapiens)
Phosphorylated OPTN translocates to the nucleus (Homo sapiens)
p-S177-OPTN [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96CV9 OPTN
Gene Names
OPTN, FIP2, GLC1E, HIP7, HYPL, NRP
Chain
chain:1-577
Reference Genes
BioGPS Gene:10133 OPTN
COSMIC (genes):OPTN OPTN
CTD Gene:10133 OPTN
dbSNP Gene:10133 OPTN
ENSEMBL:ENSG00000123240 OPTN
ENSEMBL_homo_sapiens_GENE:ENSG00000123240.17 OPTN
HGNC:17142 OPTN
KEGG Gene (Homo sapiens):10133 OPTN
Monarch:10133 OPTN
NCBI Gene:10133 OPTN
OMIM:602432 OPTN
UCSC:Q96CV9 OPTN
Reference Transcript
RefSeq:NM_001008212.1 OPTN
RefSeq:NM_001008211.1 OPTN
RefSeq:NM_021980.4 OPTN
RefSeq:NM_001008213.1 OPTN
Other Identifiers
10133
11736020_a_at
11745271_x_at
11757341_s_at
16702547
202073_PM_at
202073_at
202074_PM_s_at
202074_s_at
3235730
3235731
3235732
3235737
3235738
3235739
3235742
3235743
3235744
3235746
3235749
3235750
3235752
3235755
3235757
3235759
3235761
3235762
3235767
3235768
3235769
3235771
41742_s_at
41743_i_at
41744_at
7926239
A_14_P127414
A_23_P1461
A_33_P3333317
GE82633
GE84788
GE85528
GO:0000139
GO:0001920
GO:0002376
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005773
GO:0005776
GO:0005794
GO:0005802
GO:0005829
GO:0006914
GO:0007005
GO:0007030
GO:0007165
GO:0008104
GO:0008219
GO:0010508
GO:0016192
GO:0023052
GO:0030674
GO:0031410
GO:0031593
GO:0034067
GO:0034620
GO:0042802
GO:0043001
GO:0043122
GO:0043124
GO:0043226
GO:0045087
GO:0046872
GO:0048471
GO:0050829
GO:0055037
GO:0055038
GO:0060090
GO:0061734
GO:0070530
GO:0072659
GO:0090161
GO:0098542
GO:1904417
HMNXSV003045739
Hs.278898.0.A2_3p_at
ILMN_2381899
PH_hs_0024518
TC10000097.hg
g11415041_3p_s_at
Participates
as an output of
Phosphorylated OPTN translocates to the nucleus (Homo sapiens)
This entity regulates
Positively
Myosin phosphatase dephosphorylates PLK1
(Homo sapiens)
Other forms of this molecule
OPTN [recycling endosome membrane]
p-S177-OPTN [cytosol]
OPTN [Golgi membrane]
OPTN [cytosol]
p-S177,S473,S513-OPTN [cytosol]
Inferred To
phospho-OPTN [nucleoplasm]
(Bos taurus)
phospho-OPTN [nucleoplasm]
(Canis familiaris)
phospho-optn [nucleoplasm]
(Xenopus tropicalis)
phospho-p-S177-OPTN [nucleoplasm]
(Danio rerio)
phospho-p-S177-OPTN [nucleoplasm]
(Drosophila melanogaster)
phospho-p-S177-OPTN [nucleoplasm]
(Gallus gallus)
phospho-p-S177-OPTN [nucleoplasm]
(Mus musculus)
phospho-p-S177-OPTN [nucleoplasm]
(Rattus norvegicus)
phospho-p-S177-OPTN [nucleoplasm]
(Sus scrofa)
Modified Residues
Name
O-phospho-L-serine at 177
Coordinate
177
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_068815.2
,
NP_001008214.1
,
NP_001008213.1
,
NP_001008212.1
OpenTargets
ENSG00000123240
GeneCards
Q96CV9
HPA
ENSG00000123240-OPTN
Ensembl
ENST00000263036
,
ENST00000378752
,
ENST00000378764
,
ENST00000378757
,
ENSP00000263036
,
ENSP00000368027
,
ENSP00000368022
,
ENSP00000368032
,
ENSP00000368040
,
ENSG00000123240
,
ENST00000378747
,
ENSP00000368021
,
ENST00000378748
PRO
Q96CV9
Pharos - Targets
Q96CV9
Orphanet
16595
PDB
2LO4
,
5EOF
,
3VTW
,
5EOA
,
5B83
,
2LUE
,
5AAZ
,
7CZM
,
3VTV
Interactors (197)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15025 TNIP1
1
TNIP1 [cytosol]
(R-HSA-5690853)
0.966
22
UniProt:Q9Y3C0 WASC3
0.951
17
UniProt:Q96CV9 OPTN
6
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [cytosol]
(R-HSA-9687907)
p-S177,S473,S513-OPTN [cytosol]
(R-HSA-9687840)
0.928
16
UniProt:Q9UHD2 TBK1
5
pS-172,K48polyUb-TBK1 [cytosol]
(R-HSA-3249397)
p-TBK1 [cytosol]
(R-HSA-9008705)
K63polyUb-K30,K401-TBK1 [cytosol]
(R-HSA-9730430)
TBK1 [cytosol]
(R-HSA-166267)
p-S172-TBK1 [cytosol]
(R-HSA-168379)
0.926
17
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.824
15
UniProt:Q8TC07 TBC1D15
1
TBC1D15 [cytosol]
(R-HSA-8854150)
0.805
9
UniProt:Q9UJX2 CDC23
2
CDC23 [cytosol]
(R-HSA-174137)
CDC23 [nucleoplasm]
(R-HSA-174228)
0.795
8
UniProt:Q9NTZ6 RBM12
0.782
7
UniProt:Q9HA65 TBC1D17
1
TBC1D17 [recycling endosome]
(R-HSA-8854149)
0.74
7
UniProt:Q9BS34 ZNF670
1
ZNF670 [nucleoplasm]
(R-HSA-2248887)
0.718
6
UniProt:Q15038 DAZP2
0.718
6
UniProt:Q8IYU2 HACE1
1
HACE1 [cytosol]
(R-HSA-8851654)
0.693
15
UniProt:Q96NC0 ZMAT2
1
ZMAT2 [nucleoplasm]
(R-HSA-9770248)
0.675
4
UniProt:Q8N448 LNX2
0.668
3
UniProt:Q9BUY5 ZNF426
1
ZNF426 [nucleoplasm]
(R-HSA-1247530)
0.666
4
UniProt:P61006 RAB8A
6
GGC-RAB8A [cytoplasmic vesicle membrane]
(R-HSA-1445093)
RAB8A [recycling endosome membrane]
(R-HSA-8854145)
GGC-RAB8A [trans-Golgi network membrane]
(R-HSA-8876082)
GGC-RAB8A [cytosol]
(R-HSA-8874063)
RAB8A [Golgi membrane]
(R-HSA-2562535)
RAB8A [cytosol]
(R-HSA-5623399)
0.633
4
UniProt:Q96FJ2 DYNLL2
4
DYNLL2 [cytosol]
(R-HSA-2029024)
DYNLL2 [plasma membrane]
(R-HSA-140527)
DYNLL2 [cilium]
(R-HSA-5624865)
DYNLL2 [ciliary tip]
(R-HSA-5625337)
0.615
3
UniProt:Q29122 MYO6
0.598
3
UniProt:P54845-1 NRL
0.589
6
UniProt:Q13501 SQSTM1
7
SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711967)
SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711954)
K7 ub-SQSTM1 [cytosol]
(R-HSA-9759088)
p-S349 SQSTM1 [cytosol]
(R-HSA-9766524)
ub K420 p-S349 SQSTM1 [cytosol]
(R-HSA-9766536)
SQSTM1 [nucleoplasm]
(R-HSA-210961)
SQSTM1 [cytosol]
(R-HSA-193937)
0.558
7
UniProt:Q96EF9 ZHX1R
0.556
3
UniProt:O95340 PAPSS2
4
PAPSS2 T48R [cytosol]
(R-HSA-3621821)
PAPSS2 S438* [cytosol]
(R-HSA-3621745)
PAPSS2 R329* [cytosol]
(R-HSA-3621810)
PAPSS2 [cytosol]
(R-HSA-3009048)
0.556
3
UniProt:Q96MN9-2 Q96MN92
0.556
3
UniProt:Q8WXF7 ATLA1
0.556
3
UniProt:Q15797 SMAD1
4
Ub-SMAD1 [cytosol]
(R-HSA-6782768)
SMAD1 [cytosol]
(R-HSA-201468)
p-S463,S465-SMAD1 [cytosol]
(R-HSA-201464)
p-S463,S465-SMAD1 [nucleoplasm]
(R-HSA-201483)
0.556
3
UniProt:Q9Y574-2 Q9Y5742
0.556
3
UniProt:Q96RQ9 IL4I1
1
IL4I1 [extracellular region]
(R-HSA-2160467)
0.556
3
UniProt:Q9HBL8 NMRAL1
1
NMRAL1 [cytosol]
(R-HSA-6810879)
0.556
3
UniProt:Q71DI3 H3C15
20
2xAcK-HIST2H3A [nucleoplasm]
(R-HSA-427525)
Me1K5-HIST2H3A [nucleoplasm]
(R-HSA-9677679)
Me2aR27-HIST2H3A [nucleoplasm]
(R-HSA-5229057)
Me2aR18-HIST2H3A [nucleoplasm]
(R-HSA-5229063)
Me2sR9-HIST2H3A [nucleoplasm]
(R-HSA-5211327)
Me2sR3-HIST2H3A [nucleoplasm]
(R-HSA-5218930)
AcK9,14-p-S10-HIST2H3A [nucleoplasm]
(R-HSA-8870892)
AcK14,18,79-p-S10-HIST2H3A [nucleoplasm]
(R-HSA-8871273)
AcK9,14,18-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8871304)
AcK14,18-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8871292)
AcK9,14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8865607)
AcK14,18-p-S10-HIST2H3A [nucleoplasm]
(R-HSA-8871296)
AcK14,18,79-p-T11-HIST2H3A [nucleoplasm]
(R-HSA-8871290)
AcK14,18-p-T11-HIST2H3A [nucleoplasm]
(R-HSA-8871302)
AcK14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8871289)
Me2K28-HIST2H3A [nucleoplasm]
(R-HSA-4754197)
MeK37-HIST2H3A [nucleoplasm]
(R-HSA-4722131)
MeK80-HIST2H3A [nucleoplasm]
(R-HSA-5649805)
Me3K80-HIST2H3A [nucleoplasm]
(R-HSA-5649798)
Me2K80-HIST2H3A [nucleoplasm]
(R-HSA-5649803)
0.556
3
UniProt:Q86VR2 RETR3
0.556
3
UniProt:Q9BWG1 Q9BWG1
0.556
3
UniProt:Q96G97-4 BSCL2
0.556
3
UniProt:Q49A26-4 GLYR1
0.556
3
UniProt:P52306-4 RAP1GDS1
0.556
3
UniProt:O75031 HSF2B
0.556
3
UniProt:P40454 PTPA1
0.556
3
UniProt:Q9NWS9-2 ZNF446
0.556
3
UniProt:Q14847-2 LASP1
0.556
3
UniProt:Q9P2R7 SUCLA2
1
SUCLA2 [mitochondrial matrix]
(R-HSA-156624)
0.556
3
UniProt:Q92185 ST8SIA1
1
ST8SIA1 [Golgi membrane]
(R-HSA-4086283)
0.556
3
UniProt:Q6ZNA4-2 Q6ZNA42
0.556
3
UniProt:Q0P5P2 CQ067
0.556
3
UniProt:Q6NXG1-3 Q6NXG13
0.556
3
UniProt:Q9C0D3 ZY11B
0.556
3
UniProt:Q13113 PDZ1I
0.556
3
UniProt:P08758 ANXA5
2
ANXA5 [extracellular region]
(R-HSA-8862986)
ANXA5 [cytosol]
(R-HSA-8862945)
0.556
3
UniProt:Q9ULX5 RN112
0.556
3
UniProt:P15169 CPN1
1
CPN1 [extracellular region]
(R-HSA-8852824)
0.556
3
UniProt:P61026 RAB10
5
GGC-RAB10 [cytoplasmic vesicle membrane]
(R-HSA-8876076)
GGC-RAB10 [cytosol]
(R-HSA-8873783)
RAB10 [cytosol]
(R-HSA-8873669)
RAB10 [plasma membrane]
(R-HSA-6804816)
RAB10 [secretory granule membrane]
(R-HSA-6804788)
0.556
3
UniProt:Q99942 RNF5
1
RNF5 [endoplasmic reticulum membrane]
(R-HSA-975990)
0.556
3
UniProt:O95671 ASML
0.556
3
UniProt:Q8TBB0 THAP6
0.556
3
UniProt:Q9UBT3 DKK4
2
DKK4 [early endosome membrane]
(R-HSA-5368466)
DKK4 [extracellular region]
(R-HSA-3769327)
0.556
3
UniProt:Q9UDX5 MTFP1
0.556
3
UniProt:O60927 PP1RB
0.556
3
UniProt:P55058-2 PLTP
1
PLTP-2 [extracellular region]
(R-HSA-194203)
0.556
3
UniProt:P51116 FXR2
0.556
3
UniProt:P28347-2 TEAD1
0.556
3
UniProt:A1A4Y4 IRGM
0.556
3
UniProt:Q8N1C3 GBRG1
0.556
3
UniProt:P10276-2 RARA
0.556
3
UniProt:Q9NSI6-4 BRWD1
0.556
3
UniProt:Q9Y2X9 ZN281
0.556
3
UniProt:Q8IZS5 OFCC1
0.556
3
UniProt:Q8IVL6-2 P3H3
0.556
3
UniProt:Q53HV7-2 SMUG1
0.556
3
UniProt:Q8IYE1 CCD13
0.556
3
UniProt:P51608 MECP2
0.556
3
UniProt:Q96LX8 ZNF597
1
ZNF597 [nucleoplasm]
(R-HSA-2127591)
0.556
3
UniProt:Q96HQ0 ZNF419
1
ZNF419 [nucleoplasm]
(R-HSA-1247523)
0.556
3
UniProt:A2RU56 A2RU56
0.556
3
UniProt:Q0P5N6 ARL16
0.556
3
UniProt:P17021 ZNF17
1
ZNF17 [nucleoplasm]
(R-HSA-974984)
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:Q9UQ53 MGAT4B
1
MGAT4B [Golgi membrane]
(R-HSA-975921)
0.556
3
UniProt:Q8N302-2 Q8N3022
0.556
3
UniProt:Q8N205-2 SYNE4
0.556
3
UniProt:Q8N1Y9 YI025
0.556
3
UniProt:Q86UD4 ZN329
0.556
3
UniProt:Q13586 STIM1
1
STIM1 [endoplasmic reticulum membrane]
(R-HSA-434675)
0.556
3
UniProt:P26639 TARS1
1
TARS [cytosol]
(R-HSA-379682)
0.556
3
IntAct:EBI-25911396 CCSB
0.556
3
UniProt:Q9UIR0-4 Q9UIR04
0.556
3
UniProt:Q99732 LITAF
0.556
3
UniProt:Q8TBE1 CNIH3
3
CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689785)
CNIH3 [ER to Golgi transport vesicle membrane]
(R-HSA-5689783)
CNIH3 [endoplasmic reticulum membrane]
(R-HSA-5689443)
0.556
3
UniProt:P01123
20
phospho-p-T191-RAB1B [Golgi membrane]
(R-SCE-2422374)
phospho-p-T195-RAB1A [Golgi membrane]
(R-SCE-2172190)
RAB1B [Golgi membrane]
(R-SCE-2422381)
RAB1A [Golgi membrane]
(R-SCE-2167938)
RAB1B [cytosol]
(R-SCE-5685727)
RAB1A [cytosol]
(R-SCE-5685725)
RAB1A [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-SCE-6807766)
RAB1B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-SCE-6807768)
RAB1A [transport vesicle]
(R-SCE-6808796)
RAB1B [transport vesicle]
(R-SCE-6808799)
RAB43 [cytosol]
(R-SCE-6813902)
RAB19 [cytosol]
(R-SCE-8873714)
GGC-RAB19 [cytosol]
(R-SCE-8873773)
GGC-RAB43 [cytosol]
(R-SCE-8874038)
GGC-RAB1B [cytosol]
(R-SCE-8870426)
GGC-RAB1A [cytosol]
(R-SCE-8870424)
GGC-RAB1B [transport vesicle membrane]
(R-SCE-8877470)
GGC-RAB1A [transport vesicle membrane]
(R-SCE-8877472)
RAB43 [trans-Golgi network membrane]
(R-SCE-6814810)
RAB1A [endoplasmic reticulum membrane]
(R-SCE-6810974)
0.556
3
UniProt:Q96EY8 MMAB
4
MMAB E193K [mitochondrial matrix]
(R-HSA-3322150)
MMAB R191W [mitochondrial matrix]
(R-HSA-3322112)
MMAB R186W [mitochondrial matrix]
(R-HSA-3322128)
MMAB [mitochondrial matrix]
(R-HSA-2980970)
0.556
3
UniProt:P24666-2 P246662
0.556
3
UniProt:Q6XD76 ASCL4
0.556
3
UniProt:P17029 ZKSCAN1
1
ZKSCAN1 [nucleoplasm]
(R-HSA-975013)
0.556
3
UniProt:P10074 TZAP
0.556
3
UniProt:P50749 RASF2
0.556
3
UniProt:Q96GM5 SMARCD1
1
SMARCD1 [nucleoplasm]
(R-HSA-389255)
0.556
3
UniProt:O95872 GPAN1
0.556
3
UniProt:Q02556 IRF8
1
IRF8 [cytosol]
(R-HSA-1015685)
0.556
3
UniProt:Q32M92-2 Q32M922
0.556
3
UniProt:Q3KNW7 Q3KNW7
0.556
3
UniProt:Q496A3 SPAS1
0.556
3
UniProt:Q96EZ4 MYEOV
0.556
3
UniProt:Q96LL4 CH048
0.556
3
UniProt:Q8N5A5-2 ZGPAT
0.556
3
IntAct:EBI-25910725 CCSB
0.556
3
UniProt:P49450 CENPA
2
CENPA [nucleoplasm]
(R-HSA-606322)
CENPA [cytosol]
(R-HSA-375317)
0.556
3
UniProt:Q8IV33 K0825
0.556
3
UniProt:P23297 S100A1
1
S100A1 [extracellular region]
(R-HSA-6805991)
0.556
3
UniProt:Q8IZQ1-2 WDFY3
0.556
3
UniProt:O15195-2 O151952
0.556
3
UniProt:Q8WVJ2 NUDC2
0.556
3
IntAct:EBI-25911021 CCSB
0.556
3
UniProt:P07384 CAPN1
4
CAPN1 [plasma membrane]
(R-HSA-3828038)
CAPN1 [cytosol]
(R-HSA-3288367)
CAPN1 [extracellular region]
(R-HSA-6806485)
CAPN1 [ficolin-1-rich granule lumen]
(R-HSA-6801284)
0.556
3
UniProt:Q96PU8 QKI
2
QKI(1-504)-RAF1(278-648) fusion [cytosol]
(R-HSA-6802466)
QKI(1-504)-p-RAF1(278- 648) fusion [cytosol]
(R-HSA-6802546)
0.556
3
IntAct:EBI-25910851 CCSB
0.556
3
UniProt:O00203 AP3B1
4
AP3B1 [Golgi membrane]
(R-HSA-434335)
AP3B1 [cytoplasmic vesicle membrane]
(R-HSA-434197)
AP3B1(1-859)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802269)
AP3B1(1-859)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802516)
0.556
3
UniProt:I6L9D0 I6L9D0
0.556
3
UniProt:P49459 UBE2A
3
UBE2A [cytosol]
(R-HSA-947617)
Ub-C88-UBE2A [nucleoplasm]
(R-HSA-8864186)
UBE2A [nucleoplasm]
(R-HSA-8852048)
0.556
3
UniProt:Q5VZL5-4 ZMYM4
0.556
3
UniProt:Q6PCB6 ABHD17C
1
ABHD17C [plasma membrane]
(R-HSA-9647774)
0.556
3
UniProt:P04440 HLA-DPB1
9
HLA class II histocompatibility antigen, DP [lumenal side of endoplasmic reticulum membrane]
(R-HSA-2130709)
HLA class II histocompatibility antigen, DP [ER to Golgi transport vesicle membrane]
(R-HSA-2130688)
HLA class II histocompatibility antigen, DP [Golgi membrane]
(R-HSA-2214364)
HLA class II histocompatibility antigen, DP [trans-Golgi network membrane]
(R-HSA-2130397)
HLA class II histocompatibility antigen, DP [transport vesicle membrane]
(R-HSA-2130533)
HLA class II histocompatibility antigen, DP [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130390)
HLA class II histocompatibility antigen, DP [endocytic vesicle membrane]
(R-HSA-2130419)
HLA class II histocompatibility antigen, DP [lysosomal membrane]
(R-HSA-2130601)
HLA class II histocompatibility antigen, DP [plasma membrane]
(R-HSA-197648)
0.556
3
UniProt:P78424 PO6F2
0.556
3
UniProt:A2RRN7 A2RRN7
0.556
3
UniProt:Q96B67 ARRD3
0.556
3
UniProt:P61296-2 HAND2
0.556
3
UniProt:Q5TZF3-1 Q5TZF31
0.556
3
UniProt:Q9BUH6 PAXX
0.556
3
IntAct:EBI-25911486 CCSB
0.556
3
UniProt:Q13702-2 Q137022
0.556
3
UniProt:Q3SX64 CMA1D
0.556
3
UniProt:Q6IE81-3 JADE1
0.556
3
UniProt:Q9BYQ4 KRTAP9-2
1
KRTAP9-2 [cytosol]
(R-HSA-6809965)
0.556
3
UniProt:P78410 BTN3A2
1
BTN3A2 [plasma membrane]
(R-HSA-197605)
0.556
3
UniProt:Q9NY26 SLC39A1
1
SLC39A1 [plasma membrane]
(R-HSA-442329)
0.556
3
UniProt:O60711 LPXN
0.556
3
IntAct:EBI-25910368 CCSB
0.556
3
UniProt:P18206-2 VCL
0.556
3
IntAct:EBI-25910801 CCSB
0.556
3
UniProt:A4FUJ8 A4FUJ8
0.556
3
UniProt:Q6ZS81-2 Q6ZS812
0.556
3
UniProt:P40325 HUA1
0.556
3
UniProt:Q2NKQ1-4 SGSM1
0.556
3
UniProt:Q9P209 CEP72
1
CEP72 [cytosol]
(R-HSA-380321)
0.556
3
UniProt:O43829 ZBT14
0.556
3
UniProt:Q9NR11-2 ZNF302
0.556
3
UniProt:Q9Y5L3 ENTPD2
1
ENTPD2 [plasma membrane]
(R-HSA-8851088)
0.556
3
UniProt:Q12904-2 AIMP1
0.556
6
UniProt:Q8N0Y2-2 ZNF444
0.556
3
UniProt:Q5VYS8-5 TUT7
0.556
3
UniProt:Q96G46 DUS3L
0.556
3
UniProt:P28566 HTR1E
1
HTR1E [plasma membrane]
(R-HSA-390960)
0.556
3
UniProt:Q9Y6Q9-5 NCOA3
0.556
3
UniProt:Q08499-8 PDE4D
0.556
3
UniProt:Q9BUL9 RPP25
1
RPP25 [nucleoplasm]
(R-HSA-5696782)
0.556
3
UniProt:Q8TDB4 HUMMR
0.556
3
UniProt:P40302
1
PRE5 [cytosol]
(R-SCE-68724)
0.556
3
UniProt:P54274-2 TERF1
0.556
3
IntAct:EBI-25910474 CCSB
0.556
3
UniProt:Q86TI2-2 Q86TI22
0.556
3
UniProt:Q9Y2D5 PLAK2
0.556
3
UniProt:P35998 PSMC2
5
PSMC2 [secretory granule lumen]
(R-HSA-6800994)
PSMC2 [extracellular region]
(R-HSA-6806472)
PSMC2 [ficolin-1-rich granule lumen]
(R-HSA-6800421)
PSMC2 [nucleoplasm]
(R-HSA-174332)
PSMC2 [cytosol]
(R-HSA-68771)
0.556
3
UniProt:Q8TD17 ZNF398
1
ZNF398 [nucleoplasm]
(R-HSA-1247512)
0.556
3
IntAct:EBI-25851697 CCSB
0.556
3
UniProt:A0A1C3PI11 A0A1C3PI11
0.556
3
UniProt:Q9BV73 CEP250
1
CEP250 [cytosol]
(R-HSA-380263)
0.556
3
UniProt:Q9Y5Y5 PEX16
2
PEX16 [peroxisomal membrane]
(R-HSA-9603805)
PEX16 [cytosol]
(R-HSA-9603790)
0.556
3
UniProt:Q969S8 HDAC10
1
HDAC10 [nucleoplasm]
(R-HSA-351579)
0.556
3
UniProt:P07225 PROS1
8
11xCbxE-PROS1 [platelet alpha granule lumen]
(R-HSA-349762)
11xCbxE-PROS1 [extracellular region]
(R-HSA-202772)
11xCbxE-PROS1 [plasma membrane]
(R-HSA-141004)
PROS1(25-676) [endoplasmic reticulum membrane]
(R-HSA-159758)
11xCbxE-PROS1(25-676) [endoplasmic reticulum membrane]
(R-HSA-159770)
11xCbxE-PROS1(25-676) [Golgi membrane]
(R-HSA-159850)
PROS1(25-41) [Golgi lumen]
(R-HSA-159792)
11xCbxE-PROS1 [Golgi membrane]
(R-HSA-159865)
0.556
3
UniProt:Q9Y221 NIP7
1
NIP7 [nucleoplasm]
(R-HSA-6797236)
0.556
3
UniProt:Q14894 CRYM
1
CRYM [peroxisomal matrix]
(R-HSA-5693333)
0.556
3
UniProt:P52888 THOP1
1
THOP1 [cytosol]
(R-HSA-8940604)
0.556
3
UniProt:Q9NRA0 SPHK2
1
SPHK2 [cytosol]
(R-HSA-428236)
0.556
3
UniProt:Q9NWF9 RNF216
1
RNF216 [cytosol]
(R-HSA-936043)
0.556
3
UniProt:O15392 BIRC5
3
ub-BIRC5 [cytosol]
(R-HSA-8955933)
BIRC5 [nucleoplasm]
(R-HSA-4655344)
BIRC5 [cytosol]
(R-HSA-50851)
0.556
3
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.556
3
UniProt:Q96QE2 SLC2A13
1
SLC2A13 [plasma membrane]
(R-HSA-429102)
0.556
3
UniProt:P23528 CFL1
3
CFL1 [cytosol]
(R-HSA-350751)
p-S3-CFL1 [cytosol]
(R-HSA-399813)
CFL1 [extracellular region]
(R-HSA-350747)
0.556
3
UniProt:Q6YHU6 THADA
1
THADA [cytoplasm]
(R-HSA-8870282)
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.556
3
UniProt:P51582 P2RY4
1
P2RY4 [plasma membrane]
(R-HSA-417861)
0.556
3
UniProt:Q9BUB5 MKNK1
1
p-T250,T255,T385,S437-MKNK1 [cytosol]
(R-HSA-947860)
0.556
3
UniProt:Q9BUH8 BEGAIN
1
BEGAIN [cytosol]
(R-HSA-6794250)
0.556
3
UniProt:Q9H6R3 ACSS3
1
ACSS3 [mitochondrial matrix]
(R-HSA-5696385)
0.556
3
UniProt:Q13123 IK
1
IK [nucleoplasm]
(R-HSA-9770239)
0.556
3
UniProt:Q9BYZ2 LDHAL6B
1
LDHAL6B [mitochondrial matrix]
(R-HSA-6807613)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.527
2
UniProt:Q8TBZ3 WDR20
1
WDR20 [nucleoplasm]
(R-HSA-5696932)
0.527
2
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.527
2
UniProt:P61007
5
RAB8A [recycling endosome membrane]
(R-CFA-8854145)
GGC-RAB8A [trans-Golgi network membrane]
(R-CFA-8876082)
GGC-RAB8A [cytosol]
(R-CFA-8874063)
RAB8A [cytosol]
(R-CFA-5623399)
RAB8A [Golgi membrane]
(R-CFA-2562535)
0.527
2
UniProt:O75923 DYSF
1
DYSF [cytoplasmic vesicle membrane]
(R-HSA-5263626)
0.505
3
UniProt:Q00013 MPP1
1
MPP1 [plasma membrane]
(R-HSA-420423)
0.499
2
UniProt:Q99IB8-PRO_0000045599
0.488
3
UniProt:P63167 DYNLL1
6
DYNLL1 [ciliary tip]
(R-HSA-5625335)
DYNLL1 [cilium]
(R-HSA-5624863)
DYNLL1 [ficolin-1-rich granule membrane]
(R-HSA-6801518)
DYNLL1 [tertiary granule membrane]
(R-HSA-6801482)
DYNLL1 [plasma membrane]
(R-HSA-54017)
DYNLL1 [cytosol]
(R-HSA-387105)
0.483
2
UniProt:Q13023 AKAP6
0.454
2
UniProt:Q14BN4 SLMAP
0.454
2
UniProt:Q9UNH7 SNX6
0.454
2
UniProt:Q8WZ42 TTN
2
TTN [extracellular region]
(R-HSA-350729)
TTN [cytosol]
(R-HSA-350726)
0.454
2
UniProt:Q03001 DST
1
DST [plasma membrane]
(R-HSA-447008)
0.454
2
UniProt:P04275 VWF
20
VWF(23-763) [platelet alpha granule lumen]
(R-HSA-114662)
VWF Q1402P (764-2813) [extracellular region]
(R-HSA-9823711)
VWF S1394F (764-2813) [extracellular region]
(R-HSA-9823696)
VWF S1387I (764-2813) [extracellular region]
(R-HSA-9823697)
VWF S1358N (764-2813) [extracellular region]
(R-HSA-9823703)
VWF G1579R (764-1605) [extracellular region]
(R-HSA-9852786)
VWF C1099P (764-1605) [extracellular region]
(R-HSA-9852778)
VWF I1568N (764-1605) [extracellular region]
(R-HSA-9852790)
VWF G1631D (1606-2813) [extracellular region]
(R-HSA-9852788)
VWF Y1584C (764-1605) [extracellular region]
(R-HSA-9852765)
VWF I1568N (764-2813) [extracellular region]
(R-HSA-9844203)
VWF C1099P (764-2813) [extracellular region]
(R-HSA-9844221)
VWF G1631D (764-2813) [extracellular region]
(R-HSA-9844230)
VWF Y1584C (764-2813) [extracellular region]
(R-HSA-9844202)
VWF G1579R (764-2813) [extracellular region]
(R-HSA-9844214)
VWF (1606-2813) [extracellular region]
(R-HSA-9822534)
VWF(764-1605) [extracellular region]
(R-HSA-9822545)
VWF W1745C (764-2813) [extracellular region]
(R-HSA-9823611)
VWF H1786D (764-2813) [extracellular region]
(R-HSA-9823634)
VWF S1783A (764-2813) [extracellular region]
(R-HSA-9823588)
0.454
2
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