NID1 degradation by MMP3, 7

Stable Identifier
R-HSA-2533970
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Nidogen-1 (entactin) is a member of the nidogen family of basement membrane glycoproteins. It interacts with several other components of basement membranes, notably it connects the collagen and laminin networks to each other (Yurchenko & Patton 2009). MMPs 3, 7 (Mayer et al. 1993), 1, 9, (Sires et al. 1993), 12 (Gronski et al. 1997), 14, 15 (d'Ortho et al. 1997), 19 (Stracke et al. 2000) and leukocyte elastase (Mayer et al. 1993) can all degrade Nidogen-1.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
metalloendopeptidase activity of MMP3, MMP7 [extracellular region]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created