NID1 degradation by MMP3, 7

Stable Identifier
R-HSA-2533970
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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NID1 degradation by MMP3, 7
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Nidogen-1 (entactin) is a member of the nidogen family of basement membrane glycoproteins. It interacts with several other components of basement membranes, notably it connects the collagen and laminin networks to each other (Yurchenko & Patton 2009). MMPs 3, 7 (Mayer et al. 1993), 1, 9, (Sires et al. 1993), 12 (Gronski et al. 1997), 14, 15 (d'Ortho et al. 1997), 19 (Stracke et al. 2000) and leukocyte elastase (Mayer et al. 1993) can all degrade Nidogen-1.
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Catalyst Activity

metalloendopeptidase activity of MMP3, MMP7 [extracellular region]

Physical Entity
MMP3, MMP7 [extracellular region] (Homo sapiens)
Activity
metalloendopeptidase activity (GO:0004222)
Inferred From
Nid1 degradation by Mmp3, 7 (Mus musculus)
Authored
Jupe, S  (2012-08-08)
Reviewed
Ricard-Blum, S  (2013-08-13)
Created
Jupe, S  (2012-10-22)
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