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HIRA [nucleoplasm]
Stable Identifier
R-HSA-2532790
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Protein HIRA
Locations in the PathwayBrowser
Expand all
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
DNA Damage/Telomere Stress Induced Senescence (Homo sapiens)
Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Homo sapiens)
Initiation of SAHF formation (Homo sapiens)
HIRA [nucleoplasm] (Homo sapiens)
HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm] (Homo sapiens)
HIRA [nucleoplasm] (Homo sapiens)
SAHF formation (Homo sapiens)
HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm] (Homo sapiens)
HIRA [nucleoplasm] (Homo sapiens)
SAHF [nucleoplasm] (Homo sapiens)
HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm] (Homo sapiens)
HIRA [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P54198 HIRA
Gene Names
HIRA, DGCR1, HIR, TUPLE1
Chain
chain:1-1017
Reference Genes
BioGPS Gene:7290 HIRA
COSMIC (genes):HIRA HIRA
CTD Gene:7290 HIRA
dbSNP Gene:7290 HIRA
ENSEMBL:ENSG00000100084 HIRA
HGNC:4916 HIRA
KEGG Gene (Homo sapiens):7290 HIRA
Monarch:7290 HIRA
NCBI Gene:7290 HIRA
OMIM:600237 HIRA
UCSC:P54198 HIRA
Reference Transcript
RefSeq:NM_003325.3 HIRA
Other Identifiers
0001170390
11720837_a_at
11751996_a_at
11752104_a_at
16932261
217427_s_at
32706_at
3952639
3952640
3952647
3952650
3952651
3952653
3952655
3952656
3952657
3952658
3952659
3952662
3952664
3952668
3952671
3952672
3952674
3952675
3952676
3952677
3952678
3952683
3952684
3952690
3952693
3952696
3952697
3952698
7290
8074432
A_23_P154938
GE60125
GO:0000070
GO:0000228
GO:0000278
GO:0000417
GO:0000790
GO:0001085
GO:0001649
GO:0003674
GO:0003714
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006336
GO:0006351
GO:0006355
GO:0006357
GO:0007049
GO:0007059
GO:0007369
GO:0008134
GO:0008150
GO:0009058
GO:0009653
GO:0009790
GO:0016605
GO:0022607
GO:0030154
GO:0031935
GO:0032991
GO:0034641
GO:0042393
GO:0042692
GO:0043226
GO:0048856
GO:0051276
GO:0065003
GO:0070062
GO:0140014
GO:1903507
Hs.172350.1.S1_3p_a_at
ILMN_1813664
PH_hs_0025021
TC22000495.hg
Participant Of
input
Initiation of SAHF formation
hasComponent
HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm]
Inferred To
Hira [nucleoplasm] (Drosophila melanogaster)
Hira [nucleoplasm] (Mus musculus)
Hira [nucleoplasm] (Rattus norvegicus)
hip1 [nucleoplasm] (Schizosaccharomyces pombe)
HIR1 [nucleoplasm] (Saccharomyces cerevisiae)
hira-1 [nucleoplasm] (Caenorhabditis elegans)
hira [nucleoplasm] (Dictyostelium discoideum)
hira [nucleoplasm] (Xenopus tropicalis)
HIRA [nucleoplasm] (Bos taurus)
HIRA [nucleoplasm] (Canis familiaris)
HIRA [nucleoplasm] (Plasmodium falciparum)
HIRA [nucleoplasm] (Sus scrofa)
Cross References
RefSeq
NP_003316.3
OpenTargets
ENSG00000100084
GeneCards
P54198
HPA
ENSG00000100084-HIRA
Ensembl
ENSP00000263208
,
ENSP00000345350
,
ENST00000340170
,
ENST00000263208
,
ENSG00000100084
PRO
P54198
Orphanet
20679
PDB
5YJE
,
2I32
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y294 ASF1A
1
ASF1A [nucleoplasm]
(R-HSA-417169)
0.868
14
UniProt:Q9NVP2 ASF1B
0.71
4
UniProt:Q9NPG3 UBN1
1
UBN1 [nucleoplasm]
(R-HSA-2532791)
0.623
10
UniProt:P84243 H3-3A
15
MeK-H3F3A [nucleoplasm]
(R-HSA-427369)
H3F3A [extracellular region]
(R-HSA-977567)
2xAcK-H3F3A [nucleoplasm]
(R-HSA-427504)
AcK10-H3F3A [nucleoplasm]
(R-HSA-5250654)
Me2K-10-H3F3A [nucleoplasm]
(R-HSA-427324)
Me2K5,Me2aR2-H3F3A [nucleoplasm]
(R-HSA-8936573)
p-T12, Me2K-10-H3F3A [nucleoplasm]
(R-HSA-5625800)
p-T12-H3F3A [nucleoplasm]
(R-HSA-5625878)
p-T12,MeK-H3F3A [nucleoplasm]
(R-HSA-5625858)
p-T12,Me3K-10-H3F3A [nucleoplasm]
(R-HSA-5625758)
Me3K-10-H3F3A [nucleoplasm]
(R-HSA-5625747)
Me3K5-H3F3A [nucleoplasm]
(R-HSA-1214216)
H3F3A [nucleoplasm]
(R-HSA-212295)
Me3K-28-H3F3A [nucleoplasm]
(R-HSA-212282)
Me2K5-H3F3A [nucleoplasm]
(R-HSA-1214206)
0.527
2
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