Reactome | NEK6 [cytosol]

NEK6 [cytosol]

Stable Identifier

R-HSA-2530596

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Serine/threonine-protein kinase Nek6, NimA-related protein kinase 6

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HC98 NEK6

Gene Names

NEK6

Chain

chain:1-313

Reference Genes

BioGPS Gene:10783 NEK6

COSMIC - genes:NEK6 NEK6

CTD Gene:10783 NEK6

dbSNP Gene:10783 NEK6

ENSEMBL:ENSG00000119408 NEK6

HGNC:7749 NEK6

KEGG:hsa:10783 NEK6

Monarch:10783 NEK6

NCBI Gene:10783 NEK6

OMIM:604884 NEK6

UCSC:Q9HC98 NEK6

Reference Transcript

Participates

as a member of

NEK6/NEK7 [cytosol] (Homo sapiens)

Other forms of this molecule

p-S206-NEK6 [cytosol]

Inferred To

NEK6 [cytosol] (Bos taurus)

NEK6 [cytosol] (Caenorhabditis elegans)

NEK6 [cytosol] (Canis familiaris)

NEK6 [cytosol] (Gallus gallus)

NEK6 [cytosol] (Sus scrofa)

NEK6 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_024303155.1, NP_055212.2, NP_001159639.1, NP_001138473.1, XP_047278608.1, XP_047278610.1, XP_054217773.1, XP_054217771.1, XP_054217774.1, XP_054217768.1, NP_001159643.1, XP_054217775.1, XP_054217772.1, XP_016869706.1, XP_054217770.1, NP_001159642.1, NP_001159640.1, NP_001159641.1

ZINC - World Drugs

NEK6_HUMAN

Guide to Pharmacology - Targets

2121

OpenTargets

ENSG00000119408

ENSEMBL

ENSP00000319734, ENST00000545174, ENSG00000119408, ENSP00000441469, ENST00000546191, ENST00000539416, ENST00000373600, ENST00000540326, ENSP00000362705, ENSP00000441426, ENST00000373603, ENST00000320246, ENSP00000439651, ENSP00000362702, ENSP00000377749, ENSP00000442636, ENST00000394199

ZINC - Substances

NEK6_HUMAN

ZINC - Biogenic

NEK6_HUMAN

ZINC target

Q9HC98

PRO

Q9HC98

ZINC - Investigational

NEK6_HUMAN

ZINC - Metabolites

NEK6_HUMAN

HPA

ENSG00000119408-NEK6

GeneCards

NEK6

Pharos - Targets

Q9HC98

ZINC - Predictions - Purchasable

NEK6_HUMAN

HMDB Protein

HMDBP01264

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P98170 XIAP	4	XIAP [cytosol] (R-HSA-50849) K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [nucleoplasm] (R-HSA-3322366) XIAP [cytosol] (R-HSA-114444)	0.666	4
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2

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