Reactome | FCN2 trimer [extracellular region]

FCN2 trimer [extracellular region]

Stable Identifier

R-HSA-2530460

Type

Complex

Species

Homo sapiens

Compartment

extracellular region

Locations in the PathwayBrowser

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Immune System (Homo sapiens)

- Innate Immune System (Homo sapiens)
  - Complement cascade (Homo sapiens)
    - Initial triggering of complement (Homo sapiens)
      - Conversion of C2 into C2a and C2b (Homo sapiens)
        
        C4 activators [plasma membrane] (Homo sapiens)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
        
        FCN2 dodecamer [extracellular region] (Homo sapiens)
        
        FCN2 trimer [extracellular region] (Homo sapiens)
      - Conversion of C4 into C4a and C4b (Homo sapiens)
        
        C4 activators [plasma membrane] (Homo sapiens)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
        
        FCN2 dodecamer [extracellular region] (Homo sapiens)
        
        FCN2 trimer [extracellular region] (Homo sapiens)
      - Creation of C4 and C2 activators (Homo sapiens)
        
        Lectin pathway of complement activation (Homo sapiens)
        
        Activation of MASPs (Homo sapiens)
        
        MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
        
        FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Homo sapiens)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Homo sapiens)
        
        FCN2 dodecamer [extracellular region] (Homo sapiens)
        
        FCN2 trimer [extracellular region] (Homo sapiens)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
        
        FCN2 dodecamer [extracellular region] (Homo sapiens)
        
        FCN2 trimer [extracellular region] (Homo sapiens)
        
        Ficolins bind to repetitive carbohydrate structures on the target cell surface (Homo sapiens)
        
        Ficolin-2 binds to molecular patterns on the target cell surface (Homo sapiens)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Homo sapiens)
        
        FCN2 dodecamer [extracellular region] (Homo sapiens)
        
        FCN2 trimer [extracellular region] (Homo sapiens)
        
        FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Homo sapiens)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Homo sapiens)
        
        FCN2 dodecamer [extracellular region] (Homo sapiens)
        
        FCN2 trimer [extracellular region] (Homo sapiens)

Participants

components

3 x FCN2 [extracellular region] (Homo sapiens)

Participant Of

hasComponent

FCN2 dodecamer [extracellular region]

Inferred To

FCN2 trimer [extracellular region] (Bos taurus)

FCN2 trimer [extracellular region] (Canis familiaris)

FCN2 trimer [extracellular region] (Gallus gallus)

FCN2 trimer [extracellular region] (Mus musculus)

FCN2 trimer [extracellular region] (Rattus norvegicus)

FCN2 trimer [extracellular region] (Xenopus tropicalis)