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Collagen type III degradation by MMP10
Stable Identifier
R-HSA-2485111
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type III degradation by MMP10 (Homo sapiens)
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
MMP10 (Stromelysin-2) is able to degrade collagen type III (Nicholson et al. 1989).
Participants
Input
Collagen type III fibril [extracellular region]
(Homo sapiens)
Output
Cleaved collagen type III fibril [extracellular region]
(Homo sapiens)
Participates
as an event of
Collagen degradation (Homo sapiens)
Catalyst Activity
metalloendopeptidase activity of MMP10 [extracellular region]
Physical Entity
MMP10 [extracellular region]
(Homo sapiens)
Activity
metalloendopeptidase activity (GO:0004222)
Inferred From
Collagen type III degradation by MMP10 (Homo sapiens)
Authored
Jupe, S (2011-07-12)
Reviewed
Sorsa, T (2012-10-08)
Created
Jupe, S (2012-09-28)
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