Collagen type XIII binds Integrin alpha1beta1

Stable Identifier
R-HSA-2484965
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane
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Collagen type XIII binds Integrin alpha1beta1
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Integrin alpha1beta1 is a negative feedback regulator of collagen synthesis (Gardner et al. 1999). CHO cells expressing human integrin alpha1beta1, but not cells expressing integrin alpha2beta1, were able to bind recombinant human collagen type XIII, promoting cell spreading (Nykvist et al. 2000).

Literature References
PubMed ID Title Journal Year
10713152 Distinct recognition of collagen subtypes by alpha(1)beta(1) and alpha(2)beta(1) integrins. Alpha(1)beta(1) mediates cell adhesion to type XIII collagen

Nykvist, P, Heino, J, Pihlajaniemi, T, Käpylä, J, Ivaska, J, Tu, H

J Biol Chem 2000
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Orthologous Events
Collagen type XIII binds Integrin alpha1beta1 (Canis familiaris)
Collagen type XIII binds Integrin alpha1beta1 (Danio rerio)
Collagen type XIII binds Integrin alpha1beta1 (Mus musculus)
Collagen type XIII binds Integrin alpha1beta1 (Rattus norvegicus)
Authored
Jupe, S  (2012-08-08)
Reviewed
Ricard-Blum, S  (2013-08-13)
Created
Jupe, S  (2012-09-27)
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