Two molecules of FSTL3 bind an Activin dimer (Sidis et al. 2002, Stamler et al. 2008). FSTL3 has been experimentally shown to bind Activin A and Activin B (Schneyer et al. 2003). Binding of FSTL3 to Activin AB is inferred. A portion of FSTL3 is also located in the nucleus (Tortoriello et al. 2001), however FSTL3:Activin complexes have not been demonstrated in the nucleus.
Schneyer, A, Kattamuri, C, Keutmann, HT, Stamler, R, Sidis, Y, Thompson, TB
Schoen, A, Schneyer, A, Quigg, A, Sidis, Y
Holmes, WE, Schneyer, AL, Pan, Y, Tortoriello, DV, Keutmann, HT, Sidis, Y
Holmes, WE, Tortoriello, DV, Holtzman, DA, Schneyer, AL, Sidis, Y
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