Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GalHyl-COL6A2(?-1019) [extracellular region]
Stable Identifier
R-HSA-2470085
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
5-Gal-Hyl collagen alpha-2(VI) chain C-term fragment
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type VI degradation by MMP2,9,11 (Homo sapiens)
Cleaved collagen type VI fibril [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VI tetramer [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Cleaved tropocollagen type VI [extracellular region] (Homo sapiens)
Cleaved collagen alpha-2(VI) chains [extracellular region] (Homo sapiens)
GalHyl-COL6A2(?-1019) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12110 COL6A2
Gene Names
COL6A2
Chain
signal peptide:1-20, chain:21-1019
Reference Genes
BioGPS Gene:1292 COL6A2
COSMIC (genes):COL6A2 COL6A2
CTD Gene:1292 COL6A2
dbSNP Gene:1292 COL6A2
ENSEMBL:ENSG00000142173 COL6A2
HGNC:2212 COL6A2
KEGG:hsa:1292 COL6A2
Monarch:1292 COL6A2
NCBI Gene:1292 COL6A2
OMIM:120240 COL6A2
UCSC:P12110 COL6A2
Reference Transcript
RefSeq:NM_058175.2 COL6A2
RefSeq:NM_058174.2 COL6A2
RefSeq:NM_001849.3 COL6A2
RefSeq:XM_011529451.1 COL6A2
Other Identifiers
11720365_a_at
11744348_x_at
11758832_at
11758833_x_at
1292
16923890
209156_3p_s_at
209156_PM_s_at
209156_s_at
213290_PM_at
213290_at
32098_at
34802_at
3924435
3924436
3924439
3924440
3924441
3924442
3924443
3924444
3924445
3924446
3924447
3924448
3924450
3924451
3924452
3924453
3924454
3924456
3924457
3924458
3924460
3924461
3924462
3924463
3924464
3924466
3924468
3924469
3924470
3924471
3924475
3924476
3924477
3924478
3924479
3924480
3924481
3924487
3924488
3924489
3924490
3924491
3924492
3924493
3924494
3924495
8069301
A_23_P211233
A_23_P310956
A_33_P3269539
GE56382
GO:0005198
GO:0005515
GO:0005518
GO:0005576
GO:0005581
GO:0005615
GO:0005788
GO:0005886
GO:0007155
GO:0009411
GO:0009749
GO:0012501
GO:0016020
GO:0030020
GO:0030312
GO:0031012
GO:0032991
GO:0042383
GO:0043226
GO:0043491
GO:0051402
GO:0062023
GO:0070062
GO:1903561
HMNXSV003031888
Hs.159263.2.S1_3p_at
ILMN_1765017
ILMN_1783909
ILMN_1809928
M20777_at
PH_hs_0019710
PH_hs_0035939
TC21000253.hg
X15882_at
g13603393_3p_a_at
Participates
as a member of
Cleaved collagen alpha-2(VI) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-3Hyp-GalHyl-COL6A2(257-1019) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL6A2 [endoplasmic reticulum lumen]
GalHyl-COL6A2 [endoplasmic reticulum lumen]
GlcGalHyl-COL6A2 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL6A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL6A2 [endoplasmic reticulum lumen]
COL6A2 [endoplasmic reticulum lumen]
COL6A2 [extracellular region]
3x4Hyp-GalHyl-COL6A2 [extracellular region]
3x4Hyp-5Hyl-COL6A2 [extracellular region]
3x4Hyp-COL6A2 [extracellular region]
GalHyl-COL6A2 [extracellular region]
3x4Hyp-3Hyp-COL6A2 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL6A2 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL6A2 [extracellular region]
5Hyl-COL6A2 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL6A2 [extracellular region]
3x4Hyp-GlcGalHyl-COL6A2 [extracellular region]
GlcGalHyl-COL6A2 [extracellular region]
3x4Hyp-3Hyp-COL6A2(?-1019) [extracellular region]
GalHyl-COL6A2(21-?) [extracellular region]
3x4Hyp-GalHyl-COL6A2(?-1019) [extracellular region]
3x4Hyp-GlcGalHyl-COL6A2(21-?) [extracellular region]
GlcGalHyl-COL6A2(21-?) [extracellular region]
3x4Hyp-5Hyl-COL6A2(?-1019) [extracellular region]
5Hyl-COL6A2(21-?) [extracellular region]
3x4Hyp-COL6A2(?-1019) [extracellular region]
3x4Hyp-COL6A2(21-?) [extracellular region]
3x4Hyp-3Hyp-COL6A2(21-?) [extracellular region]
5Hyl-COL6A2(?-1019) [extracellular region]
3x4Hyp-GlcGalHyl-COL6A2(?-1019) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL6A2(21-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL6A2(?-1019) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL6A2(?-1019) [extracellular region]
COL6A2(21-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL6A2(21-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL6A2(?-1019) [extracellular region]
3x4Hyp-5Hyl-COL6A2(21-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL6A2(21-?) [extracellular region]
COL6A2(?-1019) [extracellular region]
3x4Hyp-GalHyl-COL6A2(21-?) [extracellular region]
GlcGalHyl-COL6A2(?-1019) [extracellular region]
5Hyl-COL6A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL6A2 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL6A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL6A2 [endoplasmic reticulum lumen]
3x4Hyp-COL6A2 [endoplasmic reticulum lumen]
Inferred To
Col6a2 [extracellular region]
(Mus musculus)
COL6A2 [extracellular region]
(Bos taurus)
COL6A2 [extracellular region]
(Sus scrofa)
GalHyl-COL6A2(?-1019) [extracellular region]
(Caenorhabditis elegans)
GalHyl-COL6A2(?-1019) [extracellular region]
(Dictyostelium discoideum)
Modified Residues
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_478055.2
,
NP_478054.2
,
XP_011527753.1
,
NP_001840.3
OpenTargets
ENSG00000142173
ENSEMBL
ENST00000300527
,
ENSP00000387115
,
ENSP00000380870
,
ENSP00000300527
,
ENST00000409416
,
ENST00000397763
HPA
ENSG00000142173-COL6A2
PRO
P12110
Pharos - Targets
P12110
GlyGen
P12110
Orphanet
COL6A2
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08253 MMP2
5
MMP2(110-660) [extracellular region]
(R-HSA-381456)
MMP2(30-660) [extracellular region]
(R-HSA-1604364)
MMP2(67-660) [extracellular region]
(R-HSA-1604345)
MMP2(30-66) [extracellular region]
(R-HSA-1604347)
MMP2(67-109) [extracellular region]
(R-HSA-1604371)
0.527
2
UniProt:P14780 MMP9
8
MMP9(107-707) [extracellular region]
(R-HSA-668812)
MMP9(20-707) [extracellular region]
(R-HSA-1604376)
MMP9(20-106) [extracellular region]
(R-HSA-1604713)
MMP9(20-59) [extracellular region]
(R-HSA-1604685)
MMP9(60-707) [extracellular region]
(R-HSA-1604726)
MMP9(60-106) [extracellular region]
(R-HSA-1604699)
MMP9 [tertiary granule lumen]
(R-HSA-6800181)
MMP9 [ficolin-1-rich granule lumen]
(R-HSA-6800973)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text