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NRF1:PPARGC1B binds the ATP5B promoter
Stable Identifier
R-HSA-2466369
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
NRF1:PPARGC1B binds the ATP5B promoter (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As inferred from mouse, PGC-1beta (PPARGC1B) binds NRF1 and coactivates genes regulated by NRF1.
Participants
Input
ATP5B gene [nucleoplasm]
(Homo sapiens)
NRF1 [nucleoplasm]
(Homo sapiens)
PPARGC1B [nucleoplasm]
(Homo sapiens)
Output
ATP5B gene:NRF1:PPARGC1B [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
Inferred From
Formation of Nrf1:Pgc-1beta (Ppargc1b) (Mus musculus)
Authored
May, B (2011-08-20)
Reviewed
Lezza, AM (2013-12-07)
Created
May, B (2012-09-09)
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