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MYO7A [cytosol]
Stable Identifier
R-HSA-2454121
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Unconventional myosin-VIIa, MYO7A_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
Inner hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
MYO7A [cytosol] (Homo sapiens)
USH1C:USH1G:MYO7A [plasma membrane] (Homo sapiens)
MYO7A [cytosol] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
Outer hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
MYO7A [cytosol] (Homo sapiens)
USH1C:USH1G:MYO7A [plasma membrane] (Homo sapiens)
MYO7A [cytosol] (Homo sapiens)
Visual phototransduction (Homo sapiens)
The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)
RPE65 isomero-hydrolyses atREs to 11cROL (Homo sapiens)
MYO7A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13402 MYO7A
Gene Names
MYO7A, USH1B
Chain
chain:1-2215
Reference Genes
BioGPS Gene:4647 MYO7A
COSMIC (genes):MYO7A MYO7A
CTD Gene:4647 MYO7A
dbSNP Gene:4647 MYO7A
ENSEMBL:ENSG00000137474 MYO7A
HGNC:7606 MYO7A
KEGG:hsa:4647 MYO7A
Monarch:4647 MYO7A
NCBI Gene:4647 MYO7A
OMIM:276903 MYO7A
UCSC:Q13402 MYO7A
Reference Transcript
RefSeq:NM_000260.3 MYO7A
RefSeq:NM_001127180.1 MYO7A
Other Identifiers
11726134_a_at
11738617_s_at
11756935_a_at
16729362
208189_PM_s_at
208189_s_at
211103_3p_at
211103_PM_at
211103_at
211104_PM_s_at
211104_s_at
33197_PM_at
33197_at
3341222
3341223
3341225
3341226
3341227
3341228
3341229
3341233
3341234
3341235
3341236
3341237
3341238
3341239
3341240
3341241
3341242
3341243
3341244
3341245
3341246
3341247
3341248
3341249
3341250
3341251
3341252
3341253
3341254
3341255
3341256
3341257
3341258
3341260
3341262
3341263
3341264
3341265
3341266
3341269
3341270
3341273
3341274
3341275
3341276
3341277
3341279
3341280
3341281
3341282
3341284
3341285
3341286
3341287
3341288
3341289
3341290
3341292
3341293
3341294
3341295
3341296
3341297
3341298
3341299
3341300
3341301
3341302
3341303
3341304
41041_s_at
4647
7942717
A_14_P129571
A_23_P422350
A_23_P98786
GE59126
GO:0000146
GO:0001750
GO:0001845
GO:0001917
GO:0003774
GO:0003779
GO:0005515
GO:0005516
GO:0005524
GO:0005737
GO:0005765
GO:0005829
GO:0005856
GO:0005902
GO:0005938
GO:0006886
GO:0006897
GO:0006909
GO:0007015
GO:0007040
GO:0007423
GO:0007600
GO:0007601
GO:0007605
GO:0008092
GO:0008104
GO:0015629
GO:0016020
GO:0016192
GO:0016324
GO:0016459
GO:0019904
GO:0030030
GO:0030048
GO:0030154
GO:0030507
GO:0031410
GO:0031477
GO:0032391
GO:0032420
GO:0042462
GO:0042470
GO:0042472
GO:0042490
GO:0042491
GO:0042802
GO:0043226
GO:0043531
GO:0044877
GO:0045202
GO:0048839
GO:0048856
GO:0050877
GO:0050953
GO:0050957
GO:0051015
GO:0051875
GO:0051904
GO:0060088
GO:0060113
GO:0060122
GO:0090102
GO:0120025
GO:0120044
GO:0140657
GO:1990435
HMNXSV003014080
HMNXSV003029923
HMNXSV003053186
ILMN_1811719
PH_hs_0024140
TC11000829.hg
U39226_at
U55209_at
g1613789_3p_a_at
g1613789_3p_at
g4505306_3p_s_at
Participates
as a component of
USH1C:USH1G:MYO7A [plasma membrane] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
This entity regulates
Positively
RPE65 isomero-hydrolyses atREs to 11cROL
(Homo sapiens)
Inferred To
MYO7A [cytosol]
(Bos taurus)
MYO7A [cytosol]
(Caenorhabditis elegans)
MYO7A [cytosol]
(Canis familiaris)
MYO7A [cytosol]
(Drosophila melanogaster)
MYO7A [cytosol]
(Rattus norvegicus)
Myo7a [cytosol]
(Mus musculus)
Homologues of MYO7A [cytosol]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENSP00000392185
,
ENST00000409619
,
ENSP00000386635
,
ENSP00000386331
,
ENST00000458637
,
ENST00000409709
OpenTargets
ENSG00000137474
HPA
ENSG00000137474-MYO7A
PRO
Q13402
Pharos - Targets
Q13402
GlyGen
Q13402
Orphanet
MYO7A
PDB
5MV9
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