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APOC3 [early endosome]
Stable Identifier
R-HSA-2429646
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome
Synonyms
apoC-III, apolipoprotein C-III
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of fat-soluble vitamins (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
LDLR transports extracellular CR:atREs to cytosol (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Homo sapiens)
CR:atREs:HSPG:apoE [early endosome] (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
CR:atREs:HSPG:apoE [early endosome] (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
NREH hydrolyses atREs to atROL and FAs (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
LDLR transports extracellular CR:atREs to cytosol (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Homo sapiens)
CR:atREs:HSPG:apoE [early endosome] (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
CR:atREs:HSPG:apoE [early endosome] (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
NREH hydrolyses atREs to atROL and FAs (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
CR:atREs [early endosome] (Homo sapiens)
CR [early endosome] (Homo sapiens)
APOC3 [early endosome] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02656 APOC3
Gene Names
APOC3
Chain
signal peptide:1-20, chain:21-99
Reference Genes
BioGPS Gene:345 APOC3
COSMIC (genes):APOC3 APOC3
CTD Gene:345 APOC3
dbSNP Gene:345 APOC3
ENSEMBL:ENSG00000110245 APOC3
HGNC:610 APOC3
KEGG:hsa:345 APOC3
Monarch:345 APOC3
NCBI Gene:345 APOC3
OMIM:107720 APOC3
UCSC:P02656 APOC3
Reference Transcript
RefSeq:NM_000040.1 APOC3
Other Identifiers
11723791_s_at
16731575
205820_PM_s_at
205820_s_at
3350656
3350657
3350658
3350659
3350660
3350661
3350662
3350664
3350665
3350666
345
36106_at
7944035
8077204
A_14_P105582
A_23_P203183
GE79025
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005768
GO:0005769
GO:0006629
GO:0006641
GO:0006869
GO:0007186
GO:0008289
GO:0010897
GO:0010903
GO:0010916
GO:0010987
GO:0010989
GO:0015485
GO:0016042
GO:0019433
GO:0030234
GO:0030312
GO:0031012
GO:0031410
GO:0032489
GO:0033344
GO:0033700
GO:0034361
GO:0034363
GO:0034366
GO:0034375
GO:0034379
GO:0034382
GO:0042157
GO:0042627
GO:0042632
GO:0043226
GO:0043691
GO:0045717
GO:0045833
GO:0048261
GO:0050995
GO:0051005
GO:0055102
GO:0060621
GO:0062023
GO:0065003
GO:0070062
GO:0070328
GO:0070653
GO:0098772
HMNXSV003041616
ILMN_1722070
TC11001042.hg
TC11002891.hg
X01388_at
g4557322_3p_at
Participates
as a component of
CR [early endosome] (Homo sapiens)
Other forms of this molecule
APOC3 [extracellular region]
Inferred To
APOC3 [early endosome]
(Bos taurus)
APOC3 [early endosome]
(Canis familiaris)
APOC3 [early endosome]
(Sus scrofa)
Apoc3 [early endosome]
(Mus musculus)
Apoc3 [early endosome]
(Rattus norvegicus)
Cross References
ENSEMBL
ENST00000227667
,
ENSP00000227667
OpenTargets
ENSG00000110245
HPA
ENSG00000110245-APOC3
PRO
P02656
Pharos - Targets
P02656
GlyGen
P02656
Orphanet
APOC3
HMDB Protein
HMDBP01987
PDB
2JQ3
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
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