Dystroglycan binds NRXN1

Stable Identifier
R-HSA-2426263
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Dystroglycan binds neurexin
ReviewStatus
5/5
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Dystroglycan binds NRXN1
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Dystroglycan binds specifically to a subset of neurexin LNS domains in a tight interaction that requires the glycosylation of dystroglycan and is regulated by neurexin alternative splicing. Alpha-dystroglycan binds G domain-like sequences in neurexin-1-alpha (NRXN1) (Sugita et al. 2001).
Participants
Input
Output
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as an event of
Inferred From
Dystroglycan binds Nrxn1 (Rattus norvegicus)
Authored
Jupe, S  (2012-07-31)
Reviewed
Ricard-Blum, S  (2013-05-22)
Created
Jupe, S  (2012-07-31)
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