SREBP1A,1C,2 binds the ACACA promoter

Stable Identifier
R-HSA-2426160
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
SREBF1A,1C,2 binds the ACACA promoter
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SREBP1A (SREBF1A) or SREBP1C bind two sites in the promoter of the ACACA gene (Magana et al. 1997, Rome et al. 2008). Each site is required for activation of transcription.

Literature References
PubMed ID Title Journal Year
9300785 Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins

MagaƱa, MM, Lin, SS, Dooley, KA, Osborne, TF

J Lipid Res 1997
18559965 Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle

Rome, S, Lecomte, V, Meugnier, E, Rieusset, J, Debard, C, Euthine, V, Vidal, H, Lefai, E

Physiol Genomics 2008
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