SREBP1A,1C,2 binds the ACACA promoter

Stable Identifier
R-HSA-2426160
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SREBF1A,1C,2 binds the ACACA promoter
ReviewStatus
5/5
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SREBP1A,1C,2 binds the ACACA promoter
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SREBP1A (SREBF1A) or SREBP1C bind two sites in the promoter of the ACACA gene (Magana et al. 1997, Rome et al. 2008). Each site is required for activation of transcription.

Literature References
PubMed ID Title Journal Year
18559965 Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle

Euthine, V, Lefai, E, Meugnier, E, Vidal, H, Debard, C, Rome, S, Rieusset, J, Lecomte, V

Physiol Genomics 2008
9300785 Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins

Osborne, TF, Lin, SS, Dooley, KA, Magaña, MM

J Lipid Res 1997
Participants
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Output
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Authored
May, B  (2012-07-26)
Reviewed
Liang, G  (2012-08-26)
Created
May, B  (2012-07-27)
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