Me2Se is methylated to Me3Se+ by INMT

Stable Identifier
R-HSA-2408554
Type
Reaction
Species
Homo sapiens
Compartment
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Indolethylamine N-methyltransferase (INMT) is involved in the methylation of dimethyl selenide (Me2Se) into trimethylselenonium (Me3Se+) in tandem with S-adenosylmethionine (AdoMet) transforming into S-adenosylhomocysteine (AdoHcy). This reaction is inferred from the event in mouse (Mozier et al. 1988).

Literature References
PubMed ID Title Journal Year
3350800 S-adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme in sulfur and selenium metabolism

McConnell, KP, Mozier, NM, Hoffman, JL

J. Biol. Chem. 1988
Participants
Participates
Catalyst Activity

dimethyl selenide methyltransferase activity of INMT [cytosol]

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