AdeSeHCys is hydrolysed to SeHCys by AHCY

Stable Identifier
R-HSA-2408532
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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AdeSeHCys is hydrolysed to SeHCys by AHCY
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Adenosylhomocysteinase (AHCY) is involved in the hydrolysis of adenosylselenohomocysteine (AdeSeHCys) into adenosine and selenohomocysteine (SeHCys). This reaction is inferred from the event in rat involving the protein adenosylhomocysteinase (Ahcy) (Kajander et al. 1991, Kajander and Raina 1981).

Literature References
PubMed ID Title Journal Year
1711890 Metabolism, cellular actions, and cytotoxicity of selenomethionine in cultured cells

Akerman, KK, Kärenlampi, SO, Martikainen, H, Harvima, RJ, Kajander, EO, Kantola, M, Eloranta, TO

Biol Trace Elem Res 1991
7305945 Affinity-chromatographic purification of S-adenosyl-L-homocysteine hydrolase. Some properties of the enzyme from rat liver

Raina, AM, Kajander, EO

Biochem. J. 1981
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Catalyst Activity

adenosylselenohomocysteinase activity of AHCY [cytosol]

Physical Entity
AHCY [cytosol] (Homo sapiens)
Activity
adenosylselenohomocysteinase activity (GO:0098604)
Inferred From
AdeSeHCys is hydrolysed to SeHCys by Ahcy (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
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