Parenchymal atROL translocates to HSCs

Stable Identifier
R-HSA-2404144
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Synonyms
atROL delivered to stellate cells for storage
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When the body is in a retinoid-sufficient state, all-trans-retinol (atROL) is transferred to hepatic stellate cells (HSCs) for storage. The transfer was established in rat experiments (Blomhoff et al. 1982, Blomhoff et al. 1984). The mechanism of transport is as yet unknown.

Literature References
PubMed ID Title Journal Year
6420172 Newly administered [3H]retinol is transferred from hepatocytes to stellate cells in liver for storage

Blomhoff, R, Holte, K, Naess, L, Berg, T

Exp. Cell Res. 1984
6961410 In vivo uptake of chylomicron [3H]retinyl ester by rat liver: evidence for retinol transfer from parenchymal to nonparenchymal cells

Blomhoff, R, Helgerud, P, Rasmussen, M, Berg, T, Norum, KR

Proc. Natl. Acad. Sci. U.S.A. 1982
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