Formation of lysyl-pyridinoline cross-links

Stable Identifier
R-HSA-2395322
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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Formation of lysyl-pyridinoline cross-links
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Lysyl-pyridinoline (L-Pyr) cross-links are formed from two hydroxylysine residues and a lysine residue (LKNL plus a further hydroxyallysine contributed by HLKNL), found mostly in calcified tissues (Bailey et al. 1998).

Literature References
PubMed ID Title Journal Year
6129847 Collagen cross-linking: lysyl oxidase dependent synthesis of pyridinoline in vitro: confirmation that pyridinoline is derived from collagen

Fu, JC, Uto, N, Siegel, RC, Horiuchi, K, Fujimoto, D

Biochem. Biophys. Res. Commun. 1982
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Orthologous Events
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Formation of lysyl-pyridinoline cross-links (Canis familiaris)
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Formation of lysyl-pyridinoline cross-links (Gallus gallus)
Formation of lysyl-pyridinoline cross-links (Mus musculus)
Formation of lysyl-pyridinoline cross-links (Rattus norvegicus)
Formation of lysyl-pyridinoline cross-links (Sus scrofa)
Formation of lysyl-pyridinoline cross-links (Xenopus tropicalis)
Authored
Jupe, S  (2012-04-30)
Reviewed
Raleigh, S  (2012-10-08)
Ricard-Blum, S  (2012-11-19)
Kalamajski, S  (2012-10-08)
Created
Jupe, S  (2012-06-29)
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