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GPAM gene [nucleoplasm]
Stable Identifier
R-HSA-2393968
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
Coactivators are recruited to liganded PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
Corepressors are released from liganded PPARG:RXRA heterodimer (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:H3K4me1-nucleosomes:MLL4-ASCOM,(MLL3-ASCOM) [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:H3K4me1-nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:H3K4me1-nucleosomes:MLL4-ASCOM,(MLL3-ASCOM) [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:H3K4me1-nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes:MLL4-ASCOM,(MLL3-ASCOM) [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
MLL4-ASCOM,(MLL3-ASCOM) complex is recruited to ligand- and coactivator-bound PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes:MLL4-ASCOM,(MLL3-ASCOM) [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA heterodimer binds target gene loci (Homo sapiens)
Adipogenesis target genes of PPARG and MLL3/4:Nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RXRA binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound p-Y78,Y102-PPARG2:Ligand-bound RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:NCoR/SMRT:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates estrogen receptor mediated transcription (Homo sapiens)
GPAM gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the GPAM gene enhancer (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
Activation of gene expression by SREBF (SREBP) (Homo sapiens)
Expression of Glycerol-3-phosphate Acyltransferase (GPAM, GPAT) (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
SREBP1A,1C:NF-Y:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
SREBP1A,1C binds the GPAM promoter (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
SREBP1A,1C:NF-Y:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
GPAM gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1 and ESR1 bind the GPAM gene enhancer (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000119927 GPAM
Gene Names
GPAM, GPAT1, KIAA1560
Participates
as an input of
SREBP1A,1C binds the GPAM promoter (Homo sapiens)
Expression of Glycerol-3-phosphate Acyltransferase (GPAM, GPAT) (Homo sapiens)
GPAM gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
RUNX1 and ESR1 bind the GPAM gene enhancer (Homo sapiens)
GPAM gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)
as a component of
SREBP1A,1C:NF-Y:GPAM gene [nucleoplasm] (Homo sapiens)
GPAM gene:H3K4me1-nucleosome [nucleoplasm] (Homo sapiens)
GPAM gene:nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:ESR1:estrogen:GPAM gene [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of GPAM gene [nucleoplasm]
(Bos taurus)
Ghost homologue of GPAM gene [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of GPAM gene [nucleoplasm]
(Canis familiaris)
Ghost homologue of GPAM gene [nucleoplasm]
(Danio rerio)
Ghost homologue of GPAM gene [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of GPAM gene [nucleoplasm]
(Gallus gallus)
Ghost homologue of GPAM gene [nucleoplasm]
(Mus musculus)
Ghost homologue of GPAM gene [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of GPAM gene [nucleoplasm]
(Sus scrofa)
Ghost homologue of GPAM gene [nucleoplasm]
(Xenopus tropicalis)
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