PTEN R130* [cytosol]

Stable Identifier
R-HSA-2318571
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
PTEN Arg130*
PTEN R130* [cytosol] icon
Locations in the PathwayBrowser
Participates
Other forms of this molecule
Modified Residues
Name
Nonsense mutation at L-arginine 130
Coordinate
130
PsiMod
A protein modification that effectively removes or replaces an L-arginine.
Disease
Name Identifier Synonyms
ovarian endometrioid neoplasm DOID:6212 malignant ovarian endometrioid tumor, endometrioid neoplasm of Ovary
thyroid cancer DOID:1781 Thyroid gland neoplasm, thyroid cancer, thyroid neoplasm, neoplasm of thyroid gland, thyroid neoplasm, Thyroid neoplasm, malignant tumour of thyroid gland, malignant neoplasm of thyroid gland
medulloblastoma DOID:0050902
prostate cancer DOID:10283 NGP - New growth of prostate, neoplasm of prostate (disorder), tumor of the prostate, malignant tumor of prostate (disorder), prostate neoplasm, malignant tumor of the prostate, malignant tumor of prostate (disorder), prostatic cancer, prostatic neoplasm
large intestine cancer DOID:5672 malignant Colorectal tumor, malignant neoplasm of large intestine, NOS, malignant tumor of large intestine (disorder), malignant neoplasm of colon with rectum, malignant neoplasm of large intestine NOS
leiomyosarcoma DOID:1967 leiomyosarcoma, Leiomyomosarcoma, no subtype (morphologic abnormality), leiomyosarcoma, leiomyosarcoma NOS (morphologic abnormality), Leiomyosarcomas
lung cancer DOID:1324
endometrial cancer DOID:1380 primary malignant neoplasm of endometrium, neoplasm of endometrium (disorder), endometrial neoplasm, malignant endometrial neoplasm, endometrial Ca, malignant neoplasm of endometrium, tumor of Endometrium
ovarian cancer DOID:2394 ovarian neoplasm, malignant tumour of ovary, neoplasm of ovary (disorder), ovary neoplasm, primary malignant neoplasm of ovary and other uterine adnexa (disorder), ovarian cancer, tumor of the Ovary, ovary cancer, malignant Ovarian tumor, primary ovarian cancer, malignant tumor of ovary (disorder)
cervical cancer DOID:4362 neoplasm of uterine cervix (disorder), tumor of the Cervix Uteri, cervix uteri cancer, cervical neoplasm, cervix cancer
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
brain glioma DOID:0060108
glioblastoma DOID:3068 GBM, adult glioblastoma multiforme, grade IV adult Astrocytic tumor, primary glioblastoma multiforme, spongioblastoma multiforme
Interactors (46)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O14745 NHRF1      0.826 9
 UniProt:Q5TCQ9 MAGI3      0.747 9
 UniProt:Q15599 NHRF2      0.733 6
 UniProt:P60484 PTEN  20 0.713 19
 UniProt:O60307 MAST3      0.698 4
 UniProt:P09619 PDGFRB  3 0.675 3
 UniProt:P42685 FRK  4 0.639 7
 UniProt:Q06830 PRDX1  4 0.632 7
 UniProt:P30260 CDC27  2 0.616 7
 UniProt:Q6P0Q8 MAST2      0.611 4
 UniProt:Q9NZN5-2 ARHGEF12      0.611 4
 UniProt:Q92743 HTRA1  1 0.611 4
 UniProt:Q9H5P4 PDZD7      0.611 4
 UniProt:A4D2P6 GRD2I      0.611 4
 UniProt:Q9HD26 GOPC  3 0.611 4
 UniProt:O43791 SPOP  3 0.611 4
 UniProt:Q14160 SCRIB  1 0.611 4
 UniProt:Q9Y2H9 MAST1      0.611 4
 UniProt:Q86UL8 MAGI2  1 0.611 6
 UniProt:Q9NY99 SNTG2  1 0.611 3
 UniProt:Q96L92 SNX27      0.611 4
 UniProt:Q13424 SNTA1  1 0.611 4
 UniProt:Q13884 SNTB1  1 0.611 5
 UniProt:P35226 BMI1  3 0.61 7
 UniProt:Q9R1L5 MAST1      0.593 3
 UniProt:Q60592 MAST2      0.593 4
 UniProt:P46934 NEDD4  1 0.591 4
 UniProt:O88382 MAGI2      0.581 3
 UniProt:O75970 MPDZ      0.544 4
 UniProt:Q96QZ7 MAGI1      0.544 5
 UniProt:Q15700 DLG2  2 0.544 2
 UniProt:Q8NI35 PATJ  1 0.544 3
 UniProt:P62136 PPP1CA  2 0.524 2
 UniProt:Q9JHL1 NHRF2      0.524 2
 UniProt:P21860 ERBB3      0.519 2
 UniProt:Q9NRD5 PICK1  2 0.508 2
 UniProt:Q9JK71 MAGI3      0.508 3
 UniProt:Q9P0U4 CXXC1  1 0.508 2
 UniProt:Q03135 CAV1  5 0.499 2
 UniProt:Q9ULX6 AKAP8L  1 0.499 2
 UniProt:P08238 HSP90AB1  6 0.483 2
 UniProt:Q9UER7 DAXX  13 0.483 2
 UniProt:Q16643 DBN1  1 0.471 5
 UniProt:Q9UJX3 ANAPC7  2 0.462 2
 UniProt:Q9UJX5 ANAPC4  2 0.462 2
 UniProt:Q9UJX4 ANAPC5  2 0.462 2
Cite Us!