SREBP1A,1C,2 binds SCAP:INSIG:oxysterol and is retained in the endoplasmic reticulum

Stable Identifier
R-HSA-2317531
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Synonyms
SREBF1A,1C,2 binds SCAP:INSIG:oxysterol and is retained in the endoplasmic reticulum
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

INSIG binds oxysterols and the INSIG:oxysterol complex interacts with SCAP subunits of the SREBP1A/1C/2:SCAP (SREBF1A/1C/2:SCAP) complex. This interaction retains the SREBP1A/1C/2:SCAP:INSIG:oxysterol complex in the endoplasmic reticulum. The order of assembly of the SREBP1A/1C/2:SCAP:INSIG:oxysterol complex is unknown.

Participants
Participates
Inferred From
Authored
Reviewed
Created
Cite Us!