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PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol
Stable Identifier
R-HSA-2299725
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
,
endoplasmic reticulum membrane
,
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonate metabolism (Homo sapiens)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
PGH2 moves from the endoplasmic reticulum to the cytosol. The mechanism of this movement has not been determined and could could simply be diffusion through the ER membrane. No transporter localized to intracellular membranes with specificity for PGH2 has been identified.
Literature References
PubMed ID
Title
Journal
Year
20346915
The prostaglandin transporter PGT transports PGH(2)
Chi, Y
,
Schuster, VL
Biochem. Biophys. Res. Commun.
2010
Participants
Input
PGH2 [endoplasmic reticulum lumen]
Output
PGH2 [cytosol]
Participates
as an event of
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
Authored
D'Eustachio, P (2012-06-04)
Reviewed
Rush, MG (2012-11-10)
Created
D'Eustachio, P (2012-06-04)
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