Condensin II-mediated condensation of prophase chromosomes

Stable Identifier
R-HSA-2294574
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Condensin II-mediated condensation of prophase chromosomes
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Condensation of chromosomes in prophase is mediated by chromatin-bound hyperphosphorylated condensin II complex.
Literature References
PubMed ID Title Journal Year
21498573 The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II

Abe, S, Nagasaka, K, Hirayama, Y, Kozuka-Hata, H, Oyama, M, Aoyagi, Y, Obuse, C, Hirota, T

Genes Dev. 2011
18367646 RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3

Longworth, MS, Herr, A, Ji, JY, Dyson, NJ

Genes Dev 2008
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Authored
Orlic-Milacic, M  (2013-04-23)
Reviewed
Longworth, MS  (2013-10-14)
Created
Orlic-Milacic, M  (2012-05-31)
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