Condensin II-mediated condensation of prophase chromosomes

Stable Identifier
R-HSA-2294574
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm
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Condensin II-mediated condensation of prophase chromosomes
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Condensation of chromosomes in prophase is mediated by chromatin-bound hyperphosphorylated condensin II complex.

Literature References
PubMed ID Title Journal Year
21498573 The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II

Nagasaka, K, Hirota, T, Aoyagi, Y, Abe, S, Kozuka-Hata, H, Obuse, C, Oyama, M, Hirayama, Y

Genes Dev. 2011
18367646 RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3

Herr, A, Longworth, MS, Ji, JY, Dyson, NJ

Genes Dev 2008
Participants
Input
Output
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as an event of
This event is regulated
Positively by
Regulator
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Homo sapiens)
Authored
Orlic-Milacic, M  (2013-04-22)
Reviewed
Longworth, MS  (2013-10-14)
Created
Orlic-Milacic, M  (2012-05-31)
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