RAB8A/10/13/14 release GDP and bind GTP to yield the active complex. Guanine nucleotide exchange factors (GEFs) stimulate the reaction. GTPase-activating proteins (GAPs) oppose the reaction by stimulating the intrinsic GTPase activity of the RAB proteins.
Murga-Zamalloa, CA, Atkins, SJ, Peranen, J, Swaroop, A, Khanna, H
Yoshimura, S, Gerondopoulos, A, Linford, A, Rigden, DJ, Barr, FA
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