SCARF1:ligand is endocytosed

Stable Identifier
R-HSA-2247514
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Neisseria gonorrhoeae
Compartment
plasma membrane, endocytic vesicle membrane
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SCARF1:ligand is endocytosed
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The SCARF1:ligand complex is endocytosed (Adachi et al. 1997, Berwin et al. 2004) and cross-presented on MHC class II (Murshid et al. 2010). SREC-I mediates host cell entry of Neisseria gonorrhoeae (Rechner et al. 2007)

Literature References
PubMed ID Title Journal Year
20686127 Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I

Murshid, A, Gong, J, Calderwood, SK

J. Immunol. 2010
18078691 Host glycoprotein Gp96 and scavenger receptor SREC interact with PorB of disseminating Neisseria gonorrhoeae in an epithelial invasion pathway

Rechner, C, Kühlewein, C, Müller, A, Schild, H, Rudel, T

Cell Host Microbe 2007
15371419 SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin

Berwin, B, Delneste, Y, Lovingood, RV, Post, SR, Pizzo, SV

J Biol Chem 2004
9395444 Expression cloning of a novel scavenger receptor from human endothelial cells

Adachi, H, Tsujimoto, M, Arai, H, Inoue, K

J Biol Chem 1997
Participants
Input
Output
Participant Of
hasEvent
Authored
May, B  (2013-01-27)
Neyen, C  (2013-03-22)
Reviewed
Neyen, C  (2013-03-22)
Created
May, B  (2012-05-12)
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