Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
HLA class I histocompatibility antigen, Cw-14 alpha chain [ER to Golgi transport vesicle membrane]
Stable Identifier
R-HSA-2220891
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ER to Golgi transport vesicle membrane
Synonyms
HLA-C, 1C14_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Budding of COPII coated vesicle (Homo sapiens)
COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] (Homo sapiens)
Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Homo sapiens)
monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, Cw-14 alpha chain [ER to Golgi transport vesicle membrane] (Homo sapiens)
Disassembly of COPII coated vesicle (Homo sapiens)
Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Homo sapiens)
monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, Cw-14 alpha chain [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] (Homo sapiens)
Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Homo sapiens)
monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, Cw-14 alpha chain [ER to Golgi transport vesicle membrane] (Homo sapiens)
Journey of cargo through Golgi complex (Homo sapiens)
Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Homo sapiens)
monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, Cw-14 alpha chain [ER to Golgi transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P30510 HLA-C
Gene Names
HLA-C, HLAC
Chain
signal peptide:1-24, chain:25-366
Reference Genes
BioGPS Gene:3107 HLA-C
COSMIC (genes):HLA-C HLA-C
CTD Gene:3107 HLA-C
dbSNP Gene:3107 HLA-C
ENSEMBL:ENSG00000204525.18 HLA-C
ENSEMBL:ENSG00000237022 HLA-C
KEGG Gene (Homo sapiens):3107 HLA-C
Monarch:3107 HLA-C
NCBI Gene:3107 HLA-C
UCSC:P30510 HLA-C
Reference Transcript
RefSeq:NM_002117.5 HLA-C
Participates
as a member of
Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Homo sapiens)
Other forms of this molecule
HLA class I histocompatibility antigen, Cw-14 alpha chain [Golgi membrane]
HLA class I histocompatibility antigen, Cw-14 alpha chain [phagocytic vesicle membrane]
HLA class I histocompatibility antigen, Cw-14 alpha chain [recycling endosome membrane]
HLA class I histocompatibility antigen, Cw-14 alpha chain [plasma membrane]
HLA class I histocompatibility antigen, Cw-14 alpha chain [early endosome membrane]
HLA class I histocompatibility antigen, Cw-14 alpha chain [integral component of lumenal side of endoplasmic reticulum membrane]
Cross References
RefSeq
NP_002108.4
OpenTargets
ENSG00000204525
GeneCards
P30510
PRO
P30510
Pharos - Targets
P30510
PDB
5W6A
,
1QQD
,
1IM9
,
1EFX
,
5W67
,
6PA1
,
5VGE
,
6PAG
,
3BZF
,
6JTO
,
5VGD
,
4NT6
,
5W69
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text